1. 药材主信息
| 中文名称: | 天荞麦根 |
| 英文名称: | Golden Buckwheat Root |
| 拉丁名称: | Fagopyrum cymosum [Syn. Polygonum cymosum ] |
| 使用部位: | root and rhizome |
| 功用: | To clear heat and resolve toxin, quicken blood and disperse welling abscess, dispel wind and eliminate damp. |
| 适用症: | Swelling pain in throat, sores, scrofula, hepatitis, pulmonary welling abscess, aching sinews and bones, head wind, stomachache, bacillary dysentery, Vaginal discharge. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 126622-44-4 | - | 3',4'-Methylenedioxy-7-hydroxy-6-isopentenyl flavone | 180439 |
| 79907-44-1 | 原花青素B2-3,3'-二-O-没食子酸酯 | 3,3'-Digalloylprocyanidin B2 | 124016 |
| 20315-25-7 | 原花青素B1 | Procyanidin B1 | 11250133 |
| 522-12-3 | 槲皮苷 | Quercitrin | 5280459 |
| 153-18-4 | 芦丁 | Rutin | 5280805 |
| 29836-27-9 | 山栀苷 | Shanzhiside | 11948668 |
| 110-15-6 | 琥珀酸 | Succinic Acid | 1110 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27017346 |
| CDH1 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO | 16q22.1 | 27017346 |
| CTBP1 | BARS; HADDTS | 4p16.3 | 29988033 |
| CXCL1 | FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1 | 4q13.3 | 25281414 |
| HIF1A | HIF-1-alpha; HIF-1A; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8; bHLHe78 | 14q23.2 | 31101057 |
| HSP90AA1 | EL52; HEL-S-65p; HSP86; HSP89A; HSP90A; HSP90N; HSPC1; HSPCA; HSPCAL1; HSPCAL4; HSPN; Hsp103; Hsp89; Hsp90; LAP-2; LAP2 | 14q32.31 | 31101057 |
| IFNG | IFG; IFI | 12q15 | 25281414 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 25281414 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 27017346 |
| MMP3 | CHDS6; MMP-3; SL-1; STMY; STMY1; STR1 | 11q22.2 | 29988033 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Atherosclerosis | disease | 27017346 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Ischemia | phenotype | 27017346 |
| Liver neoplasms | group | 31101057 |
| Lung Neoplasms | group | 29988033 |
| Obesity | disease | 28049156 |
| Ventricular Remodeling | phenotype | 26185015 |
