1. 药材主信息
| 中文名称: | 天花粉 |
| 英文名称: | Trichosanthes root, Skegourd root |
| 拉丁名称: | Radix Trichosanthis |
| 使用部位: | root |
| 功用: | To remove heat, to promote the production of body fluid, and to facilitate the drainage of pus and the subsidence of swelling. |
| 适用症: | Febrile diseases thirst, lung heat dry cough, diabetes mellitus due to internal heat, toxin swelling of sores, induce abortion. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 7322-31-8 | beta-D-吡喃甘露糖 | - | 439680 |
| 105279-10-5 | 柑属苷B | (2S,3R,4S,5S,6R)-2-[4-[1,3-Dihydroxy-2-[4-[(E)-3-hydroxyprop-1-enyl]-2,6-dimethoxyphenoxy]propyl]-2-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol | 11972318 |
| 3687-48-7 | - | (3R)-oct-1-en-3-ol | 6992244 |
| 24347-58-8 | (R,R)-(-)-2,3-丁二醇 | (R,R)-2,3-butanediol | 225936 |
| 66851-47-6 | - | 1,2-Benzenedi(carboxylic-14C)acid, dibutyl ester | 171810 |
| 571-61-9 | 1,5-二甲基萘 | 1,5-Dimethylnaphthalene | 11306 |
| 111-27-3 | 正己醇 | 1-Hexanol | 8103 |
| 105-67-9 | - | 2,4-Dimethylphenol | 7771 |
| 1192-62-7 | - | 2-Acetylfuran | 14505 |
| 91-57-6 | - | 2-Methylnaphthalene | 7055 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ACLY | ACL; ATPCL; CLATP | 17q21.2 | 24690568 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21440986 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 24690568 |
| CASP7 | CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3 | 10q25.3 | 24690568 |
| ERBB2 | CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1 | 17q12 | 24994678 |
| ETFDH | ETFQO; MADD | 4q32.1 | 30232818 |
| JUN | AP-1; AP1; c-Jun; cJUN; p39 | 1p32.1 | 24884571 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 21440986 |
| MIR203A | MIR203; MIRN203; hsa-mir-203a; miR-203; miRNA203; mir-203a | 14q32.33 | 24884571 |
| MTOR | FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS | 1p36.22 | 21440986 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenoma | group | 21693628 |
| Bone neoplasms | group | 21440986 |
| Brain Ischemia | disease | 30014516 |
| Brain Ischemia | disease | 24884571 |
| Colorectal Neoplasms | group | 21693628 |
| Lung Neoplasms | group | 23340170 |
| Multiple Acyl Coenzyme A Dehydrogenase Deficiency | disease | 30232818 |
| Neoplasm Metastasis | phenotype | 24994678 |
| Neoplasms | group | 28911109 |
| Neuroblastoma | disease | 24884571 |
