1. 药材主信息
| 中文名称: | 檀香 |
| 英文名称: | Sandalwood |
| 拉丁名称: | Lignum Santaii Albi |
| 使用部位: | heartwood |
| 功用: | To promote the flow of qi in the heart, to warm the spleen and stomach, to increse appetite, and to relieve pain. |
| 适用症: | Pain in chest and abdomen, cold stomachache, vomiting of water due to congealing cold qi stagnation, coronary heart disease with pattern of qi stagnation and blood stasis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 18794-84-8 | 反式-β-金合欢烯 | - | 5281517 |
| 502-61-4 | α－法呢烯 | - | 5281516 |
| 22527-23-7 | - | (+)-alpha-Santalene | 12315252 |
| 577-27-5 | - | (1aR,4R,4aS,7R,7aS,7bS)-1,1,4,7-tetramethyl-2,3,4a,5,6,7,7a,7b-octahydro-1aH-cyclopropa[e]azulen-4-ol | 92812 |
| 17430-12-5 | - | (3R,6E)-nerolidol | 11241545 |
| 115-71-9 | - | (Z)-5-[(1S,3R)-2,3-dimethyl-3-tricyclo[2.2.1.02,6]heptanyl]-2-methylpent-2-en-1-ol | 24832102 |
| 10067-29-5 | - | (Z)-Lanceol | 15560069 |
| 96-54-8 | - | 1-Methylpyrrole | 7304 |
| 18465-99-1 | 1-Monolinolenin | 1-Monolinolenoyl-rac-glycerol | 5367328 |
| 108-08-7 | - | 2,4-Dimethylpentane | 7907 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21871133 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 21871133 |
| CAMK2G | CAMK; CAMK-II; CAMKG; MRD59 | 10q22.2 | 31138329 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21951288 |
| CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | 2q33.1 | 21951288 |
| CAT | - | 11p13 | 29179721 |
| CCNB1 | CCNB | 5q13.2 | 31590241 |
| CD274 | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; hPD-L1 | 9p24.1 | 27378243 |
| CDC37 | P50CDC37 | 19p13.2 | 21871133 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Blood Pressure | phenotype | 28143892 |
| Blood Pressure | phenotype | 25076013 |
| Colorectal Neoplasms | group | 23824743 |
| Diabetes | disease | 28707095 |
| Epilepsy | disease | 29925377 |
| Epstein-Barr Virus Infections | group | 28056971 |
| Fibrosis | phenotype | 28143892 |
| Hyperglycemia | disease | 28707095 |
| Hypoxia-Ischemia, Brain | disease | 29925377 |
