1. 药材主信息
| 中文名称: | 苏木 |
| 英文名称: | Sappan Caesalpinia |
| 拉丁名称: | Caesalpinia sappan |
| 使用部位: | heartwood |
| 功用: | To quicken blood and dispel stasis, disperse swelling and relieve pain. |
| 适用症: | Amenorrhea and dysmenorrhea, postpartum blood stasis, stabbing pain in chest and abdomen, swelling pain due to external injury. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 158364-86-4 | - | 1,3,4,5-Tetracaffeoylquinic acid | 5281799 |
| 557-61-9 | 1-二十八烷醇 | 1-Octacosanol | 68406 |
| 112408-67-0 | 3-去氧苏木查耳酮 | 2'-O-Methylisoliquiritigenin | 5319688 |
| 112408-68-1 | - | 3'-Deoxy-4-O-methylsappanol | 13846680 |
| 7541-49-3 | 叶绿醇 | 3,7,11,15-Tetramethyl-2-hexadecen-1-OL | 5366244 |
| 104778-16-7 | 4-O-Methylsappanol | 4-O-methylsappanol | 13888973 |
| 83162-84-9 | Bonducellin | Bonducellin | 14079439 |
| 491-71-4 | 金圣草素 | Chryseriol | 5280666 |
| 111254-18-3 | 表苏木醇 | Episappanol | 13846650 |
| 149-91-7 | 没食子酸 | Gallic Acid | 370 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| CXCL1 | FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1 | 4q13.3 | 31753028 |
| CXCL3 | CINC-2b; GRO3; GROg; MIP-2b; MIP2B; SCYB3 | 4q13.3 | 31753028 |
| CXCR2 | CD182; CDw128b; CMKAR2; IL8R2; IL8RA; IL8RB | 2q35 | 31753028 |
| LYN | JTK8; p53Lyn; p56Lyn | 8q12.1 | 23350663 |
| PIK3CG | PI3CG; PI3K; PI3Kgamma; PIK3; p110gamma; p120-PI3K | 7q22.3 | 31753028 |
| PLCG1 | NCKAP3; PLC-II; PLC1; PLC148; PLCgamma1 | 20q12 | 23350663 |
| PTGS1 | COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS | 9q33.2 | 31753028 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Aging | phenotype | 30332646 |
| Alzheimer's Disease | disease | 30447302 |
| Autoimmune Diseases | group | 31078745 |
| Longevity | phenotype | 30332646 |
| Myocarditis | disease | 31078745 |
| Platelet aggregation | phenotype | 23350663 |
| Thrombosis | phenotype | 23350663 |
