1. 药材主信息
| 中文名称: | 水蛭 |
| 英文名称: | Bigflower Cape Jasmine |
| 拉丁名称: | Gardenia jasminoides var. grandiflora |
| 使用部位: | fruit |
| 功用: | To clear heat and resolve toxin, disperse swelling and relieve pain. |
| 适用症: | Heat toxin, jaundice, nosebleed(epistaxis), nephritis with edema, sprain and contusion. |
| 毒副作用: | Slightly Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 27876-94-4 | 西红花酸；番红花酸;藏红花酸 | Crocetin | 5281232 |
| 42553-65-1 | 西红花苷I | Crocin | 5281233 |
| 150036-82-1 | - | Croomionidine | 192462 |
| 52613-28-2 | 去乙酰车叶草苷酸甲酯 | Deacetyl asperulosidic acid methyl ester | 6325021 |
| 608-66-2 | 卫矛醇 | Galactitol | 11850 |
| 29307-60-6 | 京尼平龙胆双糖苷 | Genipin 1-gentiobioside | 3082301 |
| 9001-62-1 | - | Lipase, triacylglycerol | 135534490 |
| 9005-49-6 | - | Lovenox | 772 |
| 9005-49-6 | - | Lovenox | 772 |
| 9005-49-6 | - | Lovenox | 772 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25950476 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
| BBC3 | JFY-1; JFY1; PUMA | 19q13.32 | 24389342 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 22832932 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 27472952 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 22832932 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 27472952 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Cardiac Hypertrophy | phenotype | 26845648 |
| Cardiomegaly | phenotype | 26845648 |
| Cognition Disorders | group | 21708244 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Diabetes Mellitus, Experimental | disease | 25950476 |
| Hypercholesterolemia | disease | 31911244 |
| Inflammation | phenotype | 21708244 |
| leukemia | disease | 23584398 |
