1. 药材主信息
| 中文名称: | 水龙骨 |
| 英文名称: | Japanese Polypody |
| 拉丁名称: | Polypodium niponicum |
| 使用部位: | rhizome |
| 功用: | To clear heat and disinhibit damp, quicken blood and free network vessels. |
| 适用症: | Opacity of urine, diarrhea, strangury, wind-damp impediment pain, knocks and falls. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 474-40-8 | Citrostadienol | - | 9548595 |
| 17605-67-3 | 岩藻甾醇 | (24E)-24-N-Propylidenecholesterol | 5281328 |
| 18069-14-2 | (20R,22R)-2Β,3Β,5Α,14Α,20,22,25-七羟基胆甾-7-烯-6-酮 | 2beta,3beta,5beta,14,20,22R,25-Heptahydroxycholest-7-en-6-one | 441833 |
| 3074-76-8 | - | 3-Ethyl-3-methylhexane | 18313 |
| 434-16-2 | 7-脱氢胆固醇 | 7-Dehydrocholesterol | 439423 |
| 372-75-8 | L-瓜氨酸 | Citrulline | 9750 |
| 4657-58-3 | 环木菠萝烷醇 | Cycloartanol | 12760132 |
| 511-61-5 | - | Cyclolaudenol | 101729 |
| 3604-87-3 | - | Ecdysone | 19212 |
| 21681-17-4 | - | Hopene II | 12310619 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| BAX | BCL2L4 | 19q13.33 | 24561580 |
| BAX | BCL2L4 | 19q13.33 | 28676456 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 24561580 |
| CALM3 | CALM; CAM1; CAM2; CAMB; CPVT6; CaM; CaMIII; HEL-S-72; LQT16; PHKD; PHKD3 | 19q13.32 | 28676456 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 24561580 |
| FOXO1 | FKH1; FKHR; FOXO1A | 13q14.11 | 31063760 |
| FOXO3 | AF6q21; FKHRL1; FKHRL1P2; FOXO2; FOXO3A | 6q21 | 31063760 |
| G6PD | G6PD1 | Xq28 | 29760380 |
| GCK | FGQTL3; GK; GLK; HHF3; HK4; HKIV; HXKP; LGLK; MODY2; PNDM1 | 7p13 | 26833058 |
| HDAC8 | CDA07; CDLS5; HD8; HDACL1; KDAC8; MRXS6; RPD3; WTS | Xq13.1 | 28528906 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Abdominal Pain | phenotype | 28164346 |
| Carcinogenesis | phenotype | 30120247 |
| Heart Diseases | group | 22921781 |
| Inflammation | phenotype | 30014902 |
| Inflammation | phenotype | 28676456 |
| Insulin Resistance | phenotype | 26833058 |
| Irritable Bowel Syndrome | disease | 28164346 |
| melanoma | disease | 24561580 |
| Myocardial Reperfusion Injury | phenotype | 27340138 |
| Neoplasm Metastasis | phenotype | 29760380 |
