1. 药材主信息
| 中文名称: | 熟地黄 |
| 英文名称: | Prepared Rehmannia Root |
| 拉丁名称: | Radix Rehmanniae Preparata |
| 使用部位: | steamed and sundried root |
| 功用: | To nourish n and replenish blood, reinforce the essence of life and marrow. |
| 适用症: | Blood vacuity with yellow complexion, dizziness and palpitation, menstrual disorder [=menoxenia], incessant flooding and spotting, liver-kidney yin depletion, tidal fever with night sweat, impotence and emission, sterility and infertility, limp aching lumbus and knees, tinnitus and deafness, dizzy head and vision, premature graying in beard and hair, diabetes mellitus, constipation, kidney vacuity hasty asthma. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 506-30-9 | 花生酸 | - | 10467 |
| 17283-81-7 | Dihydro-Beta-Ionone | - | 519382 |
| 52949-83-4 | - | (2S,3S,4R,5R,6S)-6-[[(4aS,7S,7aR)-7-hydroxy-7-methyl-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-1-yl]oxy]-2-(hydroxymethyl)oxane-2,3,4,5-tetrol | 6452750 |
| 6338-41-6 | 5-羟甲基-2-呋喃甲酸 | 5-Hydroxymethyl-2-furancarboxylic acid | 80642 |
| 67-47-0 | 5-羟甲基糠醛 | 5-Hydroxymethylfurfural | 237332 |
| 67-47-0 | 5-羟甲基糠醛 | 5-Hydroxymethylfurfural | 237332 |
| 124168-04-3 | 6-O-香草酰基筋骨草醇 | 6-O-Vanilloylajugol | 14396664 |
| 82509-41-9 | 8-表马钱子苷酸 | 8-Epiloganic acid | 158144 |
| 479-98-1 | 桃叶珊瑚苷 | Aucubin | 91458 |
| 112-85-6 | 二十二烷酸 | Behenic Acid | 8215 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 31378931 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 29284152 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25950476 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| ATF6 | ACHM7; ATF6A | 1q23.3 | 28655643 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Cardiac Hypertrophy | phenotype | 26845648 |
| Cardiomegaly | phenotype | 26845648 |
| Colitis | disease | 28655643 |
| Diabetes Mellitus, Experimental | disease | 25950476 |
| Diabetes Mellitus, Experimental | disease | 29284152 |
| Hypercholesterolemia | disease | 31911244 |
| Hyperglycemia | disease | 23471488 |
| Insulin Resistance | phenotype | 29284152 |
| Liver diseases | group | 24107776 |
| Lung Neoplasms | group | 29988033 |
