科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 石蒜
英文名称: Shorttube Lycoris Equivalent plant: Lycoris chinen
拉丁名称: Lycoris radiata [Syn. Amaryllis radiata]
使用部位: bulb
功用: To dispel phlegm and promote vomiting, resolve toxin and dissipate binds.
适用症: Poliomyelitis, muscle weakness, rheumatic arthritis, pain in joints due to rheumatalgia, throat wind, nipple moth, swelling pain in throat, phlegm-drool and congesting lung, food poisoning, seeper in chest and abdomen, malign sore and swelling toxin, hemorrhoids and fistulas, knocks and falls, intractable lichen, burns and scalds, snake bite.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
61891-31-4 - (+)-Galbacin 442873
507-79-9 - (1S,13S,16R,18S)-18-methoxy-15-methyl-5,7,12-trioxa-15-azapentacyclo[11.7.0.01,16.02,10.04,8]icosa-2,4(8),9,19-tetraen-13-ol 11873227
87733-81-1 - 7,3'-Dihydroxy-4'-methoxy-8-methylflavan 442358
36393-56-3 - Cathine 441457
970-74-1 表没食子儿茶素 Epigallocatechin 72277
357-70-0 加兰他敏 Galantamine 9651
477-17-8 小星石蒜 Hippeastrine 441594
495-69-2 马尿酸 Hippuric Acid 464
477-20-3 - Homolycorine 160473
21794-66-1 高芒果苷 Homomangiferin 5491388

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
EGFR ERBB; ERBB1; HER1; NISBD2; PIG61; mENA 7p11.2 30016965
HMGB1 HMG-1; HMG1; HMG3; SBP-1 13q12.3 27924158
PDCD1 CD279; PD-1; PD1; SLEB2; hPD-1; hPD-l; hSLE1 2q37.3 31462297

4. 相关疾病

疾病名称 疾病类型 参考文献
Glioblastoma disease 30016965
Multiple Myeloma disease 27924158