1. 药材主信息
| 中文名称: | 十大功劳根 |
| 英文名称: | Mahoniae Eadix |
| 拉丁名称: | - |
| 使用部位: | - |
| 功用: | - |
| 适用症: | - |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 26137-48-4 | - | 1-Isotetrandrine | 5351212 |
| 529-51-1 | 2-(3,4-二羟基苯基)-3,7-二羟基-5-甲氧基苯并吡喃-4-酮 | Azaleatin | 5281604 |
| 478-61-5 | 小檗胺 | Berbamine | 275182 |
| 2086-83-1 | 小檗碱 | Berberine | 2353 |
| 5973-06-8 | 软脂酸-β-香树精酯 | beta-Amyrin palmitate | 13915599 |
| 2259-07-6 | Epifriedelanol acetate | Epifriedelanol acetate | 13688748 |
| 525-82-6 | 黄酮 | Flavone | 10680 |
| 14682-46-3 | - | Gaillardin | 267247 |
| 3621-38-3 | 药根碱 | Jatrorrhizine | 72323 |
| 3486-67-7 | 掌叶防已碱；巴马汀 | Palmatine | 19009 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ANXA5 | ANX5; ENX2; HEL-S-7; PP4; RPRGL3 | 4q27 | 25682924 |
| BAX | BCL2L4 | 19q13.33 | 25682924 |
| BAX | BCL2L4 | 19q13.33 | 26843455 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 26843455 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21496227 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 28990249 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 26843455 |
| CASP6 | MCH2 | 4q25 | 26843455 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 26843455 |
| CCNA1 | CT146 | 13q13.3 | 25682924 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Ischemia | disease | 28186440 |
| Carcinoma, Ovarian Epithelial | disease | 28990249 |
| Diabetes Mellitus, Experimental | disease | 27067643 |
| Diabetes Mellitus, Experimental | disease | 20304443 |
| Glucose tolerance test | phenotype | 20304443 |
| Hyperglycemia | disease | 27067643 |
| Insulin Resistance | phenotype | 22019891 |
| Insulin Resistance | phenotype | 20304443 |
| Left Ventricular Hypertrophy | disease | 31371114 |
| Neoplasms, Glandular and Epithelial | group | 28990249 |
