1. 药材主信息
| 中文名称: | 升麻 |
| 英文名称: | Largetrifoliolious Bugbane Rhizome |
| 拉丁名称: | Rhizoma Cimicifugae |
| 使用部位: | rhizome |
| 功用: | To induce perspiration and promote eruption, to remove toxic heat, and to cure drooping and ptosis. |
| 适用症: | Prevention of ptosis, women’s hormone dysfunction diseases, seasonal epidemic fire toxin, mouth sore, sore pharynx, macula, cold-heat headache, swelling toxin of welling abscess and sore, center qi fall, spleen vacuity diarrhea, chronic dysentery, vaginal discharge, flooding. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 112-31-2 | 癸醛 | - | 8175 |
| 14073-97-3 | (-)-薄荷酮 | (-)-Menthone | 26447 |
| 77982-63-9 | - | (1S,5R)-6,6-dimethylnorpinan-2-one | 157139 |
| 17430-12-5 | - | (3R,6E)-nerolidol | 11241545 |
| 2363-88-4 | 反式-2,4-癸二烯醛 | 2,4-Decadienal | 5283349 |
| 21905-60-2 | - | 2-(2-Methoxyphenoxy)phenol | 572803 |
| 1197-01-9 | 1,1-Dimethyl-2-(4-Methylphenyl)Ethanol | 2-(4-Methylphenyl)propan-2-ol | 14529 |
| 1072-83-9 | 2-乙酰吡咯 | 2-Acetylpyrrole | 14079 |
| 149-30-4 | 2-巯基苯并噻唑 | 2-Mercaptobenzothiazole | 697993 |
| 18829-56-6 | 反-2-壬烯醛 | 2-Nonenal | 5283335 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| AHR | RP85; bHLHe76 | 7p21.1 | 30831189 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24486741 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31406198 |
| AMH | MIF; MIS | 19p13.3 | 23478658 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute Coronary Syndrome | disease | 23265346 |
| Acute Coronary Syndrome | disease | 29055633 |
| Acute Coronary Syndrome | disease | 27129183 |
| Adenoma | group | 21693628 |
| Angina Pectoris | phenotype | 31733140 |
| Atrial Fibrillation | disease | 25172965 |
| Atrial Fibrillation | disease | 22090167 |
| Atrial Fibrillation | disease | 24508207 |
| Atrial Fibrillation | disease | 23040570 |
| Behcet Syndrome | disease | 22632542 |