科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 山麦冬
英文名称: Liriope Root Tuber
拉丁名称: Radix Liriopes
使用部位: Liriope spicata (Thunb. )Lour. var. prolifera Y. T. Ma.;Liriope uscari (Decne. )Bailey.
功用: Treatment of dry cough caused by lung yin deficiency, cough caused by consumptive diseases, fluid deficiency and thirst, dysphoria and insomnia, constipation due to fluid deficiency of intestine.
适用症: Treatment of dry cough caused by lung yin deficiency, cough caused by consumptive diseases, fluid deficiency and thirst, dysphoria and insomnia, constipation due to fluid deficiency of intestine.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
10502-21-3 - (2R,3R)-N-[4-(diaminomethylideneamino)butyl]-5-[(E)-3-[4-(diaminomethylideneamino)butylamino]-3-oxoprop-1-enyl]-2-(4-hydroxyphenyl)-7-methoxy-2,3-dihydro-1-benzofuran-3-carboxamide 5281114
73-24-5 腺嘌呤 Adenine 190
107-43-7 甜菜碱 Betaine 247
62-49-7 2-羟基-N,N,N-三甲基乙铵 Choline 305
338-69-2 D-丙氨酸 D-alanine 71080
1783-96-6 D-天冬氨酸 D-Aspartic acid 83887
539-15-1 大麦芽碱 Hordenine 68313
472-11-7 鲁斯可皂苷元 Ruscogenin 441893
56-45-1 L-丝氨酸 Serine 5951
72-19-5 L-苏氨酸 Threonine 6288

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 21168456
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 21708244
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 24000005
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 27472952
BBC3 JFY-1; JFY1; PUMA 19q13.32 24389342
BCL2 Bcl-2; PPP1R50 18q21.33 22832932
BCL2 Bcl-2; PPP1R50 18q21.33 27472952
BCL2L1 BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 20q11.21 22832932
BCL2L1 BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 20q11.21 27472952
BIRC5 API4; EPR-1 17q25.3 22832932

4. 相关疾病