1. 药材主信息
| 中文名称: | 山地乌头 |
| 英文名称: | Country Monkshood |
| 拉丁名称: | Aconitum monticola |
| 使用部位: | - |
| 功用: | - |
| 适用症: | - |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 6836-11-9 | - | (1R,2S,4S,5R,8R,12S,16R,19S,21S)-14-ethyl-2-hydroxy-4,6,19-trimethoxy-16-methyl-9,11-dioxa-14-azaheptacyclo[10.7.2.1~2,5~.0~1,13~.0~3,8~.0~8,12~.0~16,20~]docos-21-yl acetate (non-preferred name) | 139291836 |
| 145572-44-7 | 槐果碱 | Sophocarpine | 115269 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26945965 |
| CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | 3p22.1 | 26945965 |
| GSK3B | - | 3q13.33 | 26945965 |
| ITK | EMT; LPFS1; LYK; PSCTK2 | 5q33.3 | 26945965 |
| MAPK14 | CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA | 6p21.31 | 28571917 |
| MIR21 | MIRN21; hsa-mir-21; miR-21; miRNA21 | 17q23.1 | 28571917 |
| NFKB1 | CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB | 4q24 | 29130485 |
| PTEN | 10q23del; BZS; CWS1; DEC; GLM2; MHAM; MMAC1; PTEN1; PTENbeta; TEP1 | 10q23.31 | 28571917 |
| TGFB1 | CED; DPD1; IBDIMDE; LAP; TGF-beta1; TGFB; TGFbeta | 19q13.2 | 26945965 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Head and Neck Neoplasms | group | 28571917 |
| Liver neoplasms | group | 26945965 |
