科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 沙苑子
英文名称: Flatstem Milkvetch Seed
拉丁名称: Semen Astragali Complati
使用部位: -
功用: To benefit the liver and the kidney, arrest seminal discharge, restrain urination and improve eyesight.
适用症: Treatment of back pain, nocturnal emission and premature ejaculation in deficiency syndromes of the kidney, turbid discharge with urination, excessive leukorrhea, dribbling of urine after urination, dizziness and blurred vision.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
506-30-9 花生酸 - 10467
112-31-2 癸醛 - 8175
87-72-9 L-(+)-阿拉伯糖 - 439195
506-30-9 花生酸 - 10467
524-46-9 - (+)-Adlumine 442155
25342-82-9 - (6As)-11-hydroxy-1,2,10-trimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinolinium 161487
514-95-4 - 1,5,5-Trimethyl-6-methylene-cyclohexene 578237
21637-25-2 - 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one 51402807
41917-45-7 - 5-(3,4-Methylenedioxyphenyl)pentanoic acid 5321853
550-49-2 - Adlumidine 120734

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP 10q24.2 21445586
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 29096683
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 31174572
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 28428076
BATF2 SARI 11q13.1 31174572
BAX BCL2L4 19q13.33 31174572
BCL2 Bcl-2; PPP1R50 18q21.33 22033245
CASP1 ICE; IL1BC; P45 11q22.3 31336157
CASR CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1; hCasR 3q13.33-q21.1 21445586
CDK1 CDC2; CDC28A; P34CDC2 10q21.2 22033245

4. 相关疾病