1. 药材主信息
| 中文名称: | 青黛 |
| 英文名称: | tural Indigo |
| 拉丁名称: | Indigo turalis |
| 使用部位: | - |
| 功用: | To remove toxic heat, to reduce heat in blood, and to relieve convulsions. |
| 适用症: | 1. Inhibiting leukemia7212 and many other other tumors in experimental animals2. Enhancing the fuction of reticuloendothelial system in healthy mice and promoting phagocytosis of macrophage in mice with cancer.3. It may cause abdominal pain, diarrhea or bloody stools. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 20307-14-6 | - | (2R,3R,5S,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-(1H-indol-3-yloxy)oxan-4-one | 101529308 |
| 480-93-3 | 3-羟基吲哚 | 1H-Indol-3-ol | 50591 |
| 90109-92-5 | - | 5,6-Dioxocyclohexa-1,3-diene-1-carboxylic acid | 20154716 |
| 80681-42-1 | 5-O-甲维阿斯米醇 | 5-O-Methylvisamminol | 441970 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 491-38-3 | 乙色唑 | Chromone | 10286 |
| 6624-79-9 | 正三十二醇 | Dotriacontanol | 96117 |
| 487-60-5 | 3-吲哚基-β-D-吡喃葡萄糖苷 | Indican | 441564 |
| 482-89-3 | 靛蓝 | Indigo | 10215 |
| 482-89-3 | 靛蓝 | Indigo | 10215 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AHR | RP85; bHLHe76 | 7p21.1 | 22533375 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 25790909 |
| CDK2 | CDKN2; p33(CDK2) | 12q13.2 | 25790909 |
| CDK4 | CMM3; PSK-J3 | 12q14.1 | 25790909 |
| CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | 3p22.1 | 31663659 |
| E2F1 | E2F-1; RBAP1; RBBP3; RBP3 | 20q11.22 | 31208440 |
| EGF | HOMG4; URG | 4q25 | 31663659 |
| FOXM1 | FKHL16; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH11; HNF-3; INS-1; MPHOSPH2; MPP-2; MPP2; PIG29; TRIDENT | 12p13.33 | 31208440 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 31663659 |
| MAPK14 | CSBP; CSBP1; CSBP2; CSPB1; EXIP; Mxi2; PRKM14; PRKM15; RK; SAPK2A; p38; p38ALPHA | 6p21.31 | 31663659 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Liver neoplasms | group | 31208440 |
| Lung Neoplasms | group | 23352980 |
| Skin Neoplasms | group | 31663659 |
