1. 药材主信息
| 中文名称: | 南非钩麻 |
| 英文名称: | Devil’s Clow |
| 拉丁名称: | Harpagophytum procumbens |
| 使用部位: | whole herb |
| 功用: | To relieve pain, eliminate inflammation, resolve heat. |
| 适用症: | Bronchial asthma, ileitis, ulcerative colitis, rheumatis, abnormal increase of lipoxygenase. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 87686-74-6 | 8-P-COUMAROYL-HARPAGIDE | 8-p-Coumaroylharpagide | 10324058 |
| 331-39-5 | 咖啡酸 | Caffeic Acid | 689043 |
| 140-10-3 | 肉桂酸(顺式） | Cinnamic Acid | 444539 |
| 19210-12-9 | 哈巴俄苷 | Harpagoside | 5281542 |
| 61303-13-7 | 异麦角甾苷；异类叶升麻苷 | Isoacteoside | 6476333 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 23701745 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 28616865 |
| IL6 | BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 | 7p15.3 | 28616865 |
| NOS2 | HEP-NOS; INOS; NOS; NOS2A | 17q11.2 | 28616865 |
| PPARA | NR1C1; PPAR; PPARalpha; hPPAR | 22q13.31 | 30578827 |
| PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | 1q31.1 | 28616865 |
| TFEB | ALPHATFEB; BHLHE35; TCFEB | 6p21.1 | 30578827 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 28616865 |
| Alzheimer's Disease | disease | 30578827 |
| Chromosome Aberrations | group | 23701745 |
| Edema | phenotype | 28616865 |
| melanoma | disease | 23701745 |
| Plaque, Amyloid | disease | 30578827 |
