1. 药材主信息
| 中文名称: | 墨旱莲 |
| 英文名称: | all-grass of Yerbadetajo |
| 拉丁名称: | herba ecliptae |
| 使用部位: | aerial parts |
| 功用: | To replenish the liver and the kidney, and to arrest bleeding by removing heat from blood. |
| 适用症: | Tooth mobilizing, premature graying in beard and hair, dizziness and tinnitus, limp aching lumbus and knees, yin vacuity blood heat, hemoptysis, blood ejection, duodenal bleeding, nosebleed(epistaxis), hematuria, blood dysentery, flooding and spotting, bleeding due to external injury, eczema of skin, bleeding of skin, snake bite. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 28905-12-6 | β-D-葡萄糖(含α-D-葡萄糖) | - | 64689 |
| 20549-47-7 | (+)-二氢香芹醇 | (-)-Dihydrocarveol | 443163 |
| 87145-85-5 | - | (2,2':5',2''-Terthiophene)-5-carboxylic acid | 159047 |
| 56283-68-2 | - | (3I(2),4I+/-,20I(2))-3,23-Dihydroxyolean-12-ene-28,29-dioic acid | 101297621 |
| 26905-70-4 | 2-(4-Chloro-3-hydroxy-1-butynyl)-5-(1,3-pentadiynyl)thiophene | 1-Chloro-4-(5-(penta-1,3-diyn-1-yl)thiophen-2-yl)but-3-yn-2-ol | 5315834 |
| 1081-34-1 | α-三联噻吩 | 2,2':5',2''-Terthiophene | 65067 |
| 36190-95-1 | 3''-O-甲基香豌豆苷元 | 3'-O-Methylorobol | 5319744 |
| 99-96-7 | 对羟基苯甲酸 | 4-Hydroxybenzoic acid | 135 |
| 480-44-4 | 金合欢素;刺槐素 | Acacetin | 5280442 |
| 13059-93-3 | alpha-Terthienylmethanol | alpha-Terthienylmethanol | 454740 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21871133 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24919544 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27465039 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 30158592 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 20840540 |
| BAX | BCL2L4 | 19q13.33 | 30326282 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21871133 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30326282 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 21871133 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 22114764 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 21550230 |
| Atrial Fibrillation | disease | 21906601 |
| Blood Pressure | phenotype | 28143892 |
| Epstein-Barr Virus Infections | group | 28056971 |
| Esophageal Neoplasms | group | 26603620 |
| Fibrosis | phenotype | 28143892 |
| Inflammation | phenotype | 27374313 |
| Inflammation | phenotype | 24176090 |
| Insulin Resistance | phenotype | 30158592 |
| Liver neoplasms | group | 21131551 |
