1. 药材主信息
| 中文名称: | 猫须草 |
| 英文名称: | Spicate Clerodendranthus |
| 拉丁名称: | Clerodendranthus spicatus |
| 使用部位: | whole herb |
| 功用: | To clear heat and dispel damp, expel stone and disinhibit water. |
| 适用症: | Acute nephritis, chronic nephritis, cystitis, urethral stone, rheumatic arthritis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 20736-25-8 | 二氢芥子醇 | 4-(3-Hydroxypropyl)-2,6-dimethoxyphenol | 529893 |
| 491-67-8 | 黄芩素 | Baicalein | 5281605 |
| 331-39-5 | 咖啡酸 | Caffeic Acid | 689043 |
| 3843-74-1 | 咖啡酸甲酯 | Caffeic acid methyl ester | 689075 |
| 76822-21-4 | 丹参素 | Danshensu | 11600642 |
| 102-37-4 | 咖啡酸乙酯 | Ethyl caffeate | 5317238 |
| 102-37-4 | 咖啡酸乙酯 | Ethyl caffeate | 5317238 |
| 174591-47-0 | 迷迭香酸乙酯 | Ethyl rosmarinate | 44437692 |
| 855-96-9 | 半齿泽兰素 | Eupatorin | 97214 |
| 549-07-5 | - | Insularine | 10348927 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 29555592 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
| BBC3 | JFY-1; JFY1; PUMA | 19q13.32 | 24389342 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 22832932 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 27472952 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 22832932 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 27472952 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 29555592 |
| Brain Ischemia | disease | 23414442 |
| Cardiac fibrosis | disease | 29367637 |
| Cognition Disorders | group | 21708244 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Diabetes Mellitus, Experimental | disease | 23414442 |
| Fibrosis | phenotype | 29367637 |
| Fibrosis | phenotype | 24494798 |
