1. 药材主信息
| 中文名称: | 马兜铃 |
| 英文名称: | Dutohmanspipe Fruit |
| 拉丁名称: | Fructus Aristolochiae |
| 使用部位: | fruit |
| 功用: | To remove heat from the lung and relieve cough and asthma, and to remove heat from the large intestine. |
| 适用症: | Lung heat cough asthma, phlegm congestion and hasty qi , lung vacuity enduring cough, intestinal heat bleeding from hemorrhoids, swelling pain from hemorrhoids, edema. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 13877-91-3 | 罗勒烯 | - | 5281553 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 7785-53-7 | - | (+)-alpha-Terpineol | 442501 |
| 5794-03-6 | - | (+)-Camphene | 92221 |
| 7785-26-4 | (1S)-(-)-α-蒎烯 | (-)-alpha-Pinene | 440968 |
| 6153-17-9 | - | (-)-beta-Phellandrene | 443161 |
| 20126-76-5 | (-)-4-萜品醇 | (-)-Terpinen-4-ol | 5325830 |
| 17334-55-3 | - | (1aR,7R,7aR,7bS)-1,1,7,7a-tetramethyl-2,3,5,6,7,7b-hexahydro-1aH-cyclopropa[a]naphthalene | 15560278 |
| 5655-61-8 | - | (2S,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl acetate | 44630108 |
| 17430-12-5 | - | (3R,6E)-nerolidol | 11241545 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKR1B1 | ADR; ALDR1; ALR2; AR | 7q33 | 21712449 |
| ATF6 | ACHM7; ATF6A | 1q23.3 | 29042127 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 27756327 |
| CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | 2q33.1 | 27756327 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 27756327 |
| CATSPER1 | CATSPER; SPGF7 | 11q13.1 | 28507119 |
| CEBPA | C/EBP-alpha; CEBP | 19q13.11 | 29141998 |
| CHDH | - | 3p21.1 | 31255657 |
| DDIT3 | AltDDIT3; C/EBPzeta; CEBPZ; CHOP; CHOP-10; CHOP10; GADD153 | 12q13.3 | 28780078 |
| DDIT3 | AltDDIT3; C/EBPzeta; CEBPZ; CHOP; CHOP-10; CHOP10; GADD153 | 12q13.3 | 29042127 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Birth Weight | phenotype | 27655442 |
| Body mass index | phenotype | 27655442 |
| Carcinogenesis | phenotype | 24169354 |
| Carcinogenesis | phenotype | 28027595 |
| Carcinoma | group | 24169354 |
| Choline Deficiency | disease | 31120771 |
| Colorectal Neoplasms | group | 24827130 |
| Diabetes Mellitus | group | 25411288 |
| Glucose tolerance test | phenotype | 25411288 |
| Growth Disorders | group | 27281303 |
