1. 药材主信息
| 中文名称: | 路路通 |
| 英文名称: | fruit of beautiful sweetgum |
| 拉丁名称: | Fructus Liquidambaris |
| 使用部位: | inflorescence |
| 功用: | To dispel wind and remove obstruction from the collaterals, to cause diuresis, and to stimulate menstrual discharge. |
| 适用症: | Wind-damp impediment pain, numbness in limbs, hypertonicity of limbs, pain in stomach duct and abdomen, amenorrhea, galactostasis, edema distention fullness, eczema. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 7785-53-7 | - | (+)-alpha-Terpineol | 442501 |
| 122-69-0 | - | 2-Propenoic acid, 3-phenyl-, 3-phenyl-2-propenyl ester | 31224 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 1139-30-6 | 石竹素 | Caryophyllene oxide | 1742210 |
| 1585-68-8 | 梓木内酯 | Catalpalactone | 3014018 |
| 124151-33-3 | 松柏苷 | Coniferin | 5280372 |
| 545-48-2 | 高根二醇 | Erythrodiol | 101761 |
| 149-91-7 | 没食子酸 | Gallic Acid | 370 |
| 578-86-9 | 甘草素;甘草醇 | Liquiritigenin | 114829 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
| BBC3 | JFY-1; JFY1; PUMA | 19q13.32 | 24389342 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 22832932 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 27472952 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 22832932 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 27472952 |
| BIRC5 | API4; EPR-1 | 17q25.3 | 22832932 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Cognition Disorders | group | 21708244 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Inflammation | phenotype | 21708244 |
| leukemia | disease | 23584398 |
| leukemia | disease | 21950524 |
| Liver Cirrhosis, Experimental | disease | 21168456 |
| Liver neoplasms | group | 27036874 |
| Lung Neoplasms | group | 26362062 |
