1. 药材主信息
| 中文名称: | 芦根 |
| 英文名称: | Reed rhizome |
| 拉丁名称: | Rhizoma Phragmitis |
| 使用部位: | rhizome |
| 功用: | To remove heat, to promote the production of body fluid, to relieve emesis, and to alleviate dysuria. |
| 适用症: | Febrile diseases with vexation and thirst, stomach heat vomiting, lung heat cough, pulmonary welling abscess, heat strangury with inhibited pain. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 18794-84-8 | 反式-β-金合欢烯 | - | 5281517 |
| 7785-53-7 | - | (+)-alpha-Terpineol | 442501 |
| 7632-16-8 | - | (+)-cis-Carveol | 443177 |
| 19057-60-4 | - | (2S,3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[(1S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol | 159860 |
| 5655-61-8 | - | (2S,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl acetate | 44630108 |
| 490-79-9 | 2,5-二羟基苯甲酸（龙胆酸） | 2,5-Dihydroxybenzoic acid | 3469 |
| 3117-03-1 | 2,5-二甲氧基-1,4-苯醌 | 2,5-Dimethoxy-1,4-benzoquinone | 101405 |
| 546-49-6 | - | 3,3,6-Trimethylhepta-1,5-dien-4-one | 68346 |
| 123-08-0 | 对羟基苯甲醛 | 4-Hydroxybenzaldehyde | 126 |
| 41547-82-4 | 腺苷 | Adenosine | 60961 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 30813295 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 29247826 |
| CAT | - | 11p13 | 24559844 |
| CEBPA | C/EBP-alpha; CEBP | 19q13.11 | 29141998 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenoma | group | 21693628 |
| Body Weight | phenotype | 24559844 |
| Brain Ischemia | disease | 30014516 |
| Brain Ischemia | disease | 24884571 |
| Colorectal Neoplasms | group | 21693628 |
| Liver diseases | group | 24107776 |
| Lung Neoplasms | group | 29247826 |
| Multiple Acyl Coenzyme A Dehydrogenase Deficiency | disease | 30232818 |
| Neoplasms | group | 28911109 |
| Neuroblastoma | disease | 24884571 |
