1. 药材主信息
| 中文名称: | 龙胆 |
| 英文名称: | Gentiae Radix Et Rhozima |
| 拉丁名称: | - |
| 使用部位: | root and rhizome |
| 功用: | - |
| 适用症: | Acute icterohepatitis, urinary tract infection, acute conjunctivitis, dribbling pain of urination, damp-heat jaundice, genital swelling and itch, damp-heat vaginal discharge, distended head and headache due to liver-gallbladder repletion fire, red eyes with gall, deafness, swelling in ear, pain in rib-side, bitter taste, fright wind and convulsion. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 11019-08-2 | - | (5R-trans)-5,6-Dihydro-6-((2,3,4,6-tetra-O-acetyl-beta-D-glucopyranosyl)oxy)-5-vinyl-1H,3H-pyrano(3,4-c)pyran-1-one | 114428 |
| 131985-08-5 | - | 17beta,21beta-Epoxyhopan-3-one | 636694 |
| 21233-18-1 | - | Amaroswerin | 45359883 |
| 1862-41-5 | - | Anonaine | 160597 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 477-30-5 | - | Demecolcine | 220401 |
| 1135-24-6 | 阿魏酸 | Ferulic acid | 445858 |
| 53848-05-8 | - | Gentianal | 171304 |
| 2202-12-2 | - | Gentianidine | 362908 |
| 439-89-4 | 龙胆碱 | Gentianine | 354616 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ADRB2 | ADRB2R; ADRBR; B2AR; BAR; BETA2AR | 5q32 | 26746354 |
| AKR1B1 | ADR; ALDR1; ALR2; AR | 7q33 | 21712449 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26746354 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
| BBC3 | JFY-1; JFY1; PUMA | 19q13.32 | 24389342 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 22832932 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 27472952 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Ischemia | disease | 30414381 |
| Cognition Disorders | group | 21708244 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Cystadenocarcinoma, Serous | disease | 29879497 |
| Inflammation | phenotype | 21708244 |
| leukemia | disease | 23584398 |
| leukemia | disease | 21950524 |
| Liver Cirrhosis, Experimental | disease | 21168456 |
