1. 药材主信息
| 中文名称: | 铃兰 |
| 英文名称: | Lily of Valley |
| 拉丁名称: | Convallaria keiskei [Syn. Convallaria majalis] |
| 使用部位: | whole herb with root |
| 功用: | To war m yang and disinhibit water, dispel wind and quicken blood. |
| 适用症: | Congestive cardiac failure, rheumatic heart disease, paroxysmal tachycardia, edema. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 21637-25-2 | - | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one | 51402807 |
| 3253-62-1 | - | 3-[(3S,5S,8R,9S,10R,13R,14S,17R)-5,14-dihydroxy-10-(hydroxymethyl)-13-methyl-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2H-furan-5-one | 101289682 |
| 20063-89-2 | DL-氮杂环丁烷-2-羧酸 | Azetidine-2-carboxylic acid | 17288 |
| 99-32-1 | 白屈菜酸 | Chelidonic acid | 7431 |
| 476-32-4 | 白屈菜碱 | Chelidonine | 197810 |
| 508-75-8 | 铃兰毒苷 | Convallatoxin | 441852 |
| 13473-51-3 | - | Convalloside | 114652 |
| 522-17-8 | 鱼藤素 | Deguelin | 107935 |
| 5822-57-1 | - | Desglucocheirotoxin | 16401455 |
| 7082-34-0 | - | Erysimoside | 12308885 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 21445586 |
| AURKB | AIK2; AIM-1; AIM1; ARK-2; ARK2; AurB; IPL1; PPP1R48; STK-1; STK12; STK5; aurkb-sv1; aurkb-sv2 | 17p13.1 | 29129699 |
| AURKC | AIE2; AIK3; ARK3; AurC; HEL-S-90; SPGF5; STK13; aurora-C | 19q13.43 | 29129699 |
| CASR | CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1; hCasR | 3q13.33-q21.1 | 21445586 |
| CDH1 | Arc-1; BCDS1; CD324; CDHE; ECAD; LCAM; UVO | 16q22.1 | 22986522 |
| CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | 3p22.1 | 22986522 |
| EPHB1 | ELK; EPHT2; Hek6; NET | 3q22.2 | 23291593 |
| IGF1R | CD221; IGFIR; IGFR; JTK13 | 15q26.3 | 23348700 |
| IGFBP3 | BP-53; IBP3 | 7p12.3 | 23348700 |
| KRT18 | CK-18; CYK18; K18 | 12q13.13 | 22986522 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Esophageal Neoplasms | group | 29129699 |
| Liver Neoplasms, Experimental | phenotype | 21445586 |
| Myocardial Infarction | disease | 23291593 |
| Myocardial Reperfusion Injury | phenotype | 23291593 |
| Neoplasm Metastasis | phenotype | 22986522 |
| Pancreatic Neoplasm | disease | 22986522 |
| Prostatic Neoplasms | group | 29617673 |
