1. 药材主信息
| 中文名称: | 莲子心 |
| 英文名称: | Lotus Plumule |
| 拉丁名称: | Plumula Nelumbinis |
| 使用部位: | dried plumule and radicle in seed |
| 功用: | To remove heat from the heart and calm the nerves, to restore the coordination between the heart and the kidney, to check emission, and to arrest bleeding. |
| 适用症: | Heat entering pericardium, clouded spirit with delirious speech, non-interaction of heart and kidney, insomnia and emission, blood ejection due to blood heat, hypertension. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 14400-96-5 | 4-[[(1S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl]methyl]phenol | (+)-Armepavine | 680292 |
| 106032-53-5 | - | (+)-Higenamine | 440988 |
| 51685-40-6 | - | (+)-Linalyl acetate | 6999980 |
| 1449-09-8 | 24-Methylenecycloartan-3-ol | 24-Methylenecycloartanol | 94204 |
| 16620-96-5 | - | 6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline | 27694 |
| 16620-96-5 | - | 6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline | 27694 |
| 1862-41-5 | - | Anonaine | 160597 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 465-11-2 | 日蟾毒它灵 | Gamabufotalin | 259803 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ADRB2 | ADRB2R; ADRBR; B2AR; BAR; BETA2AR | 5q32 | 26746354 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26746354 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 30922391 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 26746354 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 26746354 |
| CXCL1 | FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1 | 4q13.3 | 25281414 |
| IFNG | IFG; IFI | 12q15 | 25281414 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 25281414 |
| MPO | - | 17q22 | 25281414 |
| MTOR | FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS | 1p36.22 | 29879497 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Ischemia | disease | 30414381 |
| Brain Neoplasms | group | 30922391 |
| Colitis | disease | 25281414 |
| Cystadenocarcinoma, Serous | disease | 29879497 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetes Mellitus, Experimental | disease | 30129056 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Fatty Liver | disease | 30129056 |
| Glioblastoma | disease | 30922391 |
