1. 药材主信息
| 中文名称: | 雷丸 |
| 英文名称: | Thunder Ball |
| 拉丁名称: | omphalia |
| 使用部位: | - |
| 功用: | To kill worms. |
| 适用症: | 1. Its proteolytic enzyme is a taeniacidal agent. 2. Its alcoholic extract is an ascaricide. |
| 毒副作用: | Slightly Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 88642-92-6 | - | (+)-8-Hydroxycalamenene | 442519 |
| 2102-75-2 | 3,8-Dimethyl-5-isopropyl-2-naphthol | 7-Hydroxycadalene | 608115 |
| 482-39-3 | 阿福豆苷 | Afzelin | 5316673 |
| 2074-53-5 | 维生素 E | Alpha-Tocopherol | 14985 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 25990-10-7 | 多聚半乳糖醛酸 | D-Galacturonic Acid | 439215 |
| 16844-71-6 | 表木栓醇 | Epifriedelanol | 119242 |
| 57-87-4 | 麦角甾醇 | Ergosterol | 444679 |
| 831-61-8 | 没食子酸乙酯 | Ethyl gallate | 13250 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31678208 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| CCL3 | G0S19-1; LD78ALPHA; MIP-1-alpha; MIP1A; SCYA3 | 17q12 | 25784697 |
| CD1A | CD1; FCB6; HTA1; R4; T6 | 1q23.1 | 25784697 |
| CD80 | B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7 | 3q13.33 | 25784697 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| HIV Infections | group | 22677126 |
| Liver diseases | group | 24107776 |
| Liver Failure, Acute | disease | 27861739 |
| Multiple Myeloma | disease | 25697480 |
| Multiple Myeloma | disease | 23044853 |
| Pseudomonas Infections | group | 22020237 |
| Septic Shock | phenotype | 22020237 |
| Shock, Cardiogenic | phenotype | 22020237 |
