1. 药材主信息
| 中文名称: | 苦石莲 |
| 英文名称: | Whiteflower Caesalpinia |
| 拉丁名称: | Caesalpinia minax |
| 使用部位: | seed |
| 功用: | To clear heat and transform damp. |
| 适用症: | Wind-heat common cold, dysentery, strangury-turbidity, retching counterflow, swollen welling abscess, sore and lichen, knocks and falls, poisonous snake bite. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 204185-91-1 | Caesalmin E | Caesalmin E | 10480816 |
| 469-83-0 | 咖啡醇 | Cafestol | 108052 |
| 83-48-7 | 豆甾醇 | Stigmasterol | 5280794 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| BAX | BCL2L4 | 19q13.33 | 22734486 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 22734486 |
| BCL2L11 | BAM; BIM; BOD | 2q13 | 25375379 |
| BID | FP497 | 22q11.21 | 22734486 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Kidney Neoplasm | disease | 25375379 |
| Liver diseases | group | 24107776 |
| Lung Neoplasms | group | 22734486 |
| Mesothelioma | disease | 22734486 |
