1. 药材主信息
| 中文名称: | 苦地胆 |
| 英文名称: | Scabrous Elephantfoot |
| 拉丁名称: | Elephantopus scaber |
| 使用部位: | whole herb |
| 功用: | To clear heat, cool blood, resolve toxin, disinhibit damp. |
| 适用症: | Common cold, pertussis, tonsillitis, pharyngolaryngitis, conjunctivitis, jaundice, nephritis with edema, menstrual disorder, vaginal discharge, sore and boil, eczema, snake or insect bites. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 2259-07-6 | Epifriedelanol acetate | Epifriedelanol acetate | 13688748 |
| 545-47-1 | 羽扇豆醇 | Lupeol | 259846 |
| 486-70-4 | 羽扇豆宁 | Lupinine | 91461 |
| 83-48-7 | 豆甾醇 | Stigmasterol | 5280794 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKR1B1 | ADR; ALDR1; ALR2; AR | 7q33 | 21712449 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25260383 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| BAX | BCL2L4 | 19q13.33 | 25260383 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 25260383 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenocarcinoma | group | 22342517 |
| Liver diseases | group | 24107776 |
| Liver neoplasms | group | 25101566 |
| Mammary Neoplasms, Experimental | phenotype | 22342517 |
| Prostatic Neoplasms | group | 21712449 |
