1. 药材主信息
| 中文名称: | 金荞麦 |
| 英文名称: | Wild Buckwheat Rhizome |
| 拉丁名称: | Rhizoma Fagopyri Cymosi |
| 使用部位: | - |
| 功用: | 1. Its extractum and component flavanol promotes macrophage phagocytosis in the peritoneum of mouse.2. Flavanol is also an anti-inflammatory component. It promotes blood circulation and inhibits the agglutination of blood platelet. |
| 适用症: | 1. To clear heat and toxic material. For lung abscess, cough due to lung-heat, also for sorethroat and skin infection. 2. To promote blood circulation to eliminate blood stasis. For menorrhalgia due to blood stasis, postpartum abdominal pain due to blood |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 35323-91-2 | - | (+)-Epicatechin | 182232 |
| 18829-70-4 | (-)-儿茶素 | (-)-Catechin | 73160 |
| 130405-40-2 | 儿茶素没食子酸酯 | (-)-Catechin gallate | 6419835 |
| 19057-60-4 | - | (2S,3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[(1S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol | 159860 |
| 32899-41-5 | L-ALPHA-PALMITIN | 1-Hexadecanoyl-sn-glycerol | 3084463 |
| 54337-90-5 | 3,4-二羟基苯腈 | 3,4-Dihydroxybenzamide | 148675 |
| 123-08-0 | 对羟基苯甲醛 | 4-Hydroxybenzaldehyde | 126 |
| 387-80-4 | - | 5beta-Stigmastan-3beta-ol, (24S)- | 6451614 |
| 13186-19-1 | - | 6-O-Galloylglucose | 128839 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24157255 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 20840540 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27017346 |
| ALPL | AP-TNAP; APTNAP; HOPS; TNALP; TNAP; TNSALP | 1p36.12 | 25832436 |
| ALPP | ALP; ALPI; IAP; PALP; PLAP; PLAP-1 | 2q37.1 | 25832436 |
| ASRGL1 | ALP; ALP1; CRASH | 11q12.3 | 25832436 |
| ATHS | ALP | 19p13.3-p13.2 | 25832436 |
| ATRNL1 | ALP; bA338L11.1; bA454H24.1 | 10q25.3 | 25832436 |
| BAX | BCL2L4 | 19q13.33 | 30326282 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30326282 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenoma | group | 21693628 |
| Atherosclerosis | disease | 27017346 |
| Blood Pressure | phenotype | 25076013 |
| Brain Ischemia | disease | 30014516 |
| Brain Ischemia | disease | 24884571 |
| Colitis | disease | 25281414 |
| Colorectal Neoplasms | group | 23824743 |
| Colorectal Neoplasms | group | 21693628 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
