1. 药材主信息
| 中文名称: | 黄海棠 |
| 英文名称: | Giant StJohn’swort |
| 拉丁名称: | Hypericum ascyron |
| 使用部位: | whole herb |
| 功用: | To cool blood and stanch bleeding, quicken blood and regulate menstruation, clear heat and resolve toxin. |
| 适用症: | Blood ejection due to blood heat, hemoptysis, hematuria, hematochezia, flooding and spotting, knocks and falls, bleeding due to external injury, menstrual disorder, dysmenorrhea, galactostasis, wind-heat common cold, malaria, hepatitis, dysentery, diarrhea, poisonous snake bite, scalds, eczema, yellow-water sore. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 21637-25-2 | - | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one | 51402807 |
| 262292-34-2 | 3,6-二羟基-1,7-二甲氧基呫吨酮 | 3,6-Dihydroxy-1,7-dimethoxyxanthone | 101010505 |
| 11079-53-1 | 贯叶金丝桃素 | Hyperforin | 441298 |
| 520-18-3 | 山柰素（山柰酚） | Kaempferol | 5280863 |
| 117-39-5 | 槲皮素 | Quercetin | 5280343 |
| 153-18-4 | 芦丁 | Rutin | 5280805 |
| 23460-01-7 | - | Vinetorin | 5384285 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 21445586 |
| CASR | CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1; hCasR | 3q13.33-q21.1 | 21445586 |
| CXCL1 | FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1 | 4q13.3 | 25281414 |
| IFNG | IFG; IFI | 12q15 | 25281414 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 25281414 |
| LONP1 | CODASS; LON; LONP; LonHS; PIM1; PRSS15; hLON | 19p13.3 | 31683954 |
| MMP9 | CLG4B; GELB; MANDP2; MMP-9 | 20q13.12 | 20883786 |
| MPO | - | 17q22 | 25281414 |
| PPARGC1A | LEM6; PGC-1(alpha); PGC-1alpha; PGC-1v; PGC1; PGC1A; PPARGC1 | 4p15.2 | 28049156 |
| S100A8 | 60B8AG; CAGA; CFAG; CGLA; CP-10; L1Ag; MA387; MIF; MRP8; NIF; P8 | 1q21.3 | 25281414 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Neoplasms | group | 20883786 |
| Cerebellar Neoplasms | group | 20883786 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Glioblastoma | disease | 20883786 |
| Liver Neoplasms, Experimental | phenotype | 21445586 |
| Medulloblastoma | disease | 20883786 |
| Obesity | disease | 28049156 |
