1. 药材主信息
| 中文名称: | 黄柏 |
| 英文名称: | Amur Corktree Equivalent plant: Phellodendron chin |
| 拉丁名称: | Phellodendron amurense |
| 使用部位: | bark |
| 功用: | To drain fire, dispel damp and resolve toxin. |
| 适用症: | Damp-heat dysentery, tuberculosis, epidemic meningitis, acute conjunctivitis, trachoma, fever, abdominal pain, diarrhea, suppurative hematochezia, tenesmus, jaundice, yellow thick foul leukorrhagia, swelling pain in knees and feet, urinary tract infection, boil, sore, ulcer, eczema, mouth sore, hemorrhoids, burns, scalds, exuberance of fire with tidal fever, tidal fever with night sweat, emission. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 106-22-9 | β-香茅醇 | - | 8842 |
| 99-83-2 | 水芹烯 | - | 7460 |
| 2243-33-6 | - | (+)-alpha-Phellandrene | 443160 |
| 13837-75-7 | (Z)-limoneneoxide,cis-1,2-epoxy-p-menth-8-ene | (1R,4R,6S)-1-methyl-4-(prop-1-en-2-yl)-7-oxabicyclo[4.1.0]heptane | 6857487 |
| 751-29-1 | - | (2E)-3-[(3aS,5aR,6R,7R,9aR,9bR,10aS)-3-(Furan-3-yl)-7-(2-hydroxypropan-2-yl)-3a,6,9a-trimethyl-1,9-dioxododecahydronaphtho[2,1-c]oxireno[d]pyran-6-yl]prop-2-enoic acid | 54611038 |
| 14982-50-4 | - | (2S,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexanoic acid | 84740 |
| 25342-82-9 | - | (6As)-11-hydroxy-1,2,10-trimethoxy-6,6-dimethyl-5,6,6a,7-tetrahydro-4h-dibenzo[de,g]quinolinium | 161487 |
| 5096-57-1 | (-)-四氢小檗碱 | (S)-Canadine | 21171 |
| 483-34-1 | 四氢非洲防己碱 | (S)-Tetrahydrocolumbamine | 440229 |
| 56219-04-6 | (Z)-9-Hexadecenal | (Z)-9-Hexadecenal | 5364643 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31406198 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21168456 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21708244 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24000005 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27472952 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinoma, Ovarian Epithelial | disease | 28990249 |
| Cognition Disorders | group | 21708244 |
| Colitis | disease | 25281414 |
| Colonic Neoplasms | group | 23330808 |
| Colorectal Neoplasms | group | 27472952 |
| Colorectal Neoplasms | group | 22832932 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetes Mellitus, Experimental | disease | 27067643 |
| Diabetes Mellitus, Experimental | disease | 20304443 |
