1. 药材主信息
| 中文名称: | 槐花 |
| 英文名称: | flower bud of Japanese pagodatree |
| 拉丁名称: | flos Sophorae |
| 使用部位: | - |
| 功用: | To arrest bleeding by reducing heat in blood, and to quench excess fire in the liver. |
| 适用症: | 1. Its component rutin decreases capillay permeability. 2. Lowering blood pressure transiently in anesthetized dog. 3. Inhibiting the growth of various dermatomyces. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 112-31-2 | 癸醛 | - | 8175 |
| 506-30-9 | 花生酸 | - | 10467 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 7785-53-7 | - | (+)-alpha-Terpineol | 442501 |
| 52483-01-9 | - | (2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)-5-hydroxy-5-methyl-2-prop-1-en-2-ylhexyl]-2,3-dihydrochromen-4-one | 44563159 |
| 82793-02-0 | - | (2S,3S,4S,5R,6R)-6-[[(3S,4aR,6aR,6bS,8aR,9R,12aS,14aR,14bR)-9-hydroxy-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,4-dihydroxy-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-2-carboxylic acid | 102500449 |
| 575-43-9 | 1,6-二甲基萘 | 1,6-Dimethylnaphthalene | 11328 |
| 2363-88-4 | 反式-2,4-癸二烯醛 | 2,4-Decadienal | 5283349 |
| 581-42-0 | 2,6-二甲基萘 | 2,6-Dimethylnaphthalene | 11387 |
| 32466-54-9 | 反式-2-十二烷烯酸 | 2-Dodecenoic acid | 5282729 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26784390 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26945965 |
| BAX | BCL2L4 | 19q13.33 | 21714853 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21714853 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30822359 |
| BIRC7 | KIAP; LIVIN; ML-IAP; MLIAP; RNF50 | 20q13.33 | 21714853 |
| CAMK2G | CAMK; CAMK-II; CAMKG; MRD59 | 10q22.2 | 31138329 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21951288 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21714853 |
| CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | 2q33.1 | 21951288 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute Lung Injury | disease | 28285192 |
| Blood Pressure | phenotype | 25076013 |
| Carcinogenesis | phenotype | 28027595 |
| Colitis | disease | 25281414 |
| Colorectal Neoplasms | group | 23824743 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus | group | 30999670 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Endometriosis | disease | 22447626 |
