1. 药材主信息
| 中文名称: | 华山矾 |
| 英文名称: | Chinese Sweetleaf |
| 拉丁名称: | Symplocos chinensis |
| 使用部位: | root |
| 功用: | To clear heat and resolve toxin, transform phlegm and interrupt malaria, free network vessels and relieve pain. |
| 适用症: | Common cold with fever, diarrhea and dysentery, swelling of sores and boils, poisonous snake bites, malaria, pain in sinews and bones, knocks and falls. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 477-90-7 | 岩白菜素 | Bergenin | 66065 |
| 481-74-3 | 大黄酚 | Chrysophanic acid | 10208 |
| 95262-48-9 | 苦莓苷F1 | Niga-ichigoside F1 | 16118969 |
| 117-39-5 | 槲皮素 | Quercetin | 5280343 |
| 153-18-4 | 芦丁 | Rutin | 5280805 |
| 474-58-8 | 刺五加苷A(胡萝卜苷） | Sitogluside | 5742590 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 20840540 |
| BAX | BCL2L4 | 19q13.33 | 30326282 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30326282 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 30326282 |
| CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | 2q33.1 | 30326282 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 30326282 |
| CXCL1 | FSP; GRO1; GROa; MGSA; MGSA-a; NAP-3; SCYB1 | 4q13.3 | 25281414 |
| IFNG | IFG; IFI | 12q15 | 25281414 |
| IL10 | CSIF; GVHDS; IL-10; IL10A; TGIF | 1q32.1 | 26603620 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 26603620 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Esophageal Neoplasms | group | 26603620 |
| Melanoma, Experimental | disease | 20840540 |
| Neoplasm Metastasis | phenotype | 20840540 |
| Obesity | disease | 28049156 |
| Ventricular Remodeling | phenotype | 26185015 |
