1. 药材主信息
| 中文名称: | 厚朴 |
| 英文名称: | bark of Officil magnolia |
| 拉丁名称: | Cortex Magnoliae officilis |
| 使用部位: | - |
| 功用: | To eliminate damp and relieve distension. |
| 适用症: | 1. Broad-spectrum antibacterial.2. Magnocurarine, one of the active components, can relaxstriated muscles.3. Its decoction stimulates the smooth muscles of intestines and bronchii in rabbits in vitro.4. Magnocuraine may also lower blood pressure and accelerate heart rate. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 18794-84-8 | 反式-β-金合欢烯 | - | 5281517 |
| 498-15-7 | (1S)-(+)-3-蒈烯 | (+)-3-Carene | 443156 |
| 2243-33-6 | - | (+)-alpha-Phellandrene | 443160 |
| 5794-03-6 | - | (+)-Camphene | 92221 |
| 7632-16-8 | - | (+)-cis-Carveol | 443177 |
| 7212-44-4 | - | (+)-Nerolidol | 5356544 |
| 7212-44-4 | - | (+)-Nerolidol | 5356544 |
| 2438-10-0 | (+)-萜品-4-醇 | (+)-Terpinen-4-ol | 2724161 |
| 7785-26-4 | (1S)-(-)-α-蒎烯 | (-)-alpha-Pinene | 440968 |
| 14073-97-3 | (-)-薄荷酮 | (-)-Menthone | 26447 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ADAMTS4 | ADAMTS-2; ADAMTS-4; ADMP-1 | 1q23.3 | 29649568 |
| ADAMTS5 | ADAM-TS 11; ADAM-TS 5; ADAM-TS5; ADAMTS-11; ADAMTS-5; ADAMTS11; ADMP-2 | 21q21.3 | 29649568 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26454217 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27940017 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 30587839 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21757288 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31905887 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31406198 |
| BAX | BCL2L4 | 19q13.33 | 22259050 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute Lung Injury | disease | 21279327 |
| Brain Edema | phenotype | 30597199 |
| Brain Ischemia | disease | 30597199 |
| Brain Neoplasms | group | 22259050 |
| Cardiomegaly | phenotype | 25871545 |
| Cerebral Hemorrhage | phenotype | 30597199 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes | disease | 28707095 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
