1. 药材主信息
| 中文名称: | 红毛五加皮 |
| 英文名称: | Girald Acanthopanax Root-bark |
| 拉丁名称: | Acanthopanax giraldii [Syn. Acanthopanax giraldii |
| 使用部位: | stem cortex or root cortex |
| 功用: | To dispel wind-damp, strengthen sinews and bones, quicken blood and disinhibit water. |
| 适用症: | Wind-cold-damp impediment, hypertonicity and pain, limp wilting sinew and bone, inability of legs and knees, pain in heart and abdomen, mounting qi [=hernia], knocks and falls, fracture, vacuity and edema. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 489-39-4 | (+)-Aromadendrene | (+)-Aromadendrene | 11095734 |
| 189165-79-5 | - | (+)-delta-Amorphene | 12306059 |
| 21852-80-2 | - | (E,R)-Heptadeca-1,9-dien-4,6-diyne-3-ol | 56935896 |
| 27400-77-7 | - | 1-Nonadecene | 29075 |
| 3777-69-3 | 2-戊基呋喃 | 2-Pentylfuran | 19602 |
| 562-74-3 | 4-松油醇 | 4-Terpineol, (+/-)- | 11230 |
| 502-69-2 | 植酮 | 6,10,14-Trimethylpentadecan-2-one | 10408 |
| 41547-82-4 | 腺苷 | Adenosine | 60961 |
| 80-56-8 | α-蒎烯 | alpha-PINENE | 6654 |
| 20853-58-1 | 常春藤皂苷 D2/木通皂苷C | Cauloside C | 13878151 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 20840540 |
| ALDH3A1 | ALDH3; ALDHIII | 17p11.2 | 29794221 |
| BAX | BCL2L4 | 19q13.33 | 30326282 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 30326282 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 30326282 |
| CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | 2q33.1 | 30326282 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 30326282 |
| CNR2 | CB-2; CB2; CX5 | 1p36.11 | 31883107 |
| FGB | HEL-S-78p | 4q31.3 | 26249791 |
| IL10 | CSIF; GVHDS; IL-10; IL10A; TGIF | 1q32.1 | 26603620 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Body mass index | phenotype | 26249791 |
| Esophageal Neoplasms | group | 26603620 |
| Head and Neck Neoplasms | group | 29794221 |
| Inflammation | phenotype | 26249791 |
| Melanoma, Experimental | disease | 20840540 |
| Neoplasm Metastasis | phenotype | 20840540 |
| Xerostomia | disease | 29794221 |
