1. 药材主信息
| 中文名称: | 荷花玉兰 |
| 英文名称: | Southern Magnolia |
| 拉丁名称: | Magnolia grandiflora |
| 使用部位: | flower and bark |
| 功用: | To dispel wind and dissipate cold, move qi and relieve pain. |
| 适用症: | Externally contracted wind-cold, headache and nasal congestion, distending pain in stomach duct, vomiting and diarrhea, hypertension, tuberculosis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 58322-78-4 | - | 2-Hydroxychrysophanol | 442759 |
| 93673-81-5 | 厚朴木酚素A | 3-[4-Hydroxy-3-(2-hydroxy-5-prop-2-enylphenyl)phenyl]propane-1,2-diol | 5319201 |
| 1110-58-3 | - | 7-(8-Formyl-1,7-dihydroxy-5-isopropyl-6-methoxy-3-methyl-2-naphthyl)-2,8-dihydroxy-4-isopropyl-3-methoxy-6-methyl-naphthalene-1-carbaldehyde | 375713 |
| 118-34-3 | 紫丁香苷 | Eleutheroside B | 5316860 |
| 475-75-2 | 鹅掌楸碱 | Liriodenine | 10144 |
| 2141-09-5 | 木兰花碱 | Magnoflorine | 73337 |
| 72145-13-2 | - | Magnolialide | 636954 |
| 528-43-8 | 厚朴酚 | Magnolol | 72300 |
| 4846-19-9 | 原荷叶碱(N-去甲基荷叶碱) | N-Nornuciferine | 12313579 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21757288 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31905887 |
| BAX | BCL2L4 | 19q13.33 | 27268146 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 27268146 |
| CCND1 | BCL1; D11S287E; PRAD1; U21B31 | 11q13.3 | 21757288 |
| COL11A2 | DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3 | 6p21.32 | 27268146 |
| ERBB2 | CD340; HER-2; HER-2/neu; HER2; MLN 19; NEU; NGL; TKR1 | 17q12 | 21757288 |
| GABRG1 | - | 4p12 | 21518336 |
| IL1B | IL-1; IL1-BETA; IL1F2; IL1beta | 2q14.1 | 30597199 |
| MMP2 | CLG4; CLG4A; MMP-2; MMP-II; MONA; TBE-1 | 16q12.2 | 21757288 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Edema | phenotype | 30597199 |
| Brain Ischemia | disease | 30597199 |
| Cerebral Hemorrhage | phenotype | 30597199 |
| Inflammation | phenotype | 30597199 |
| Lung Neoplasms | group | 27268146 |
| Neoplasm Metastasis | phenotype | 21757288 |
| ovarian neoplasm | disease | 21757288 |
| Seizures | phenotype | 21518336 |
