1. 药材主信息
| 中文名称: | 汉三七 |
| 英文名称: | Sanchi |
| 拉丁名称: | Radix Notoginseng |
| 使用部位: | Panax notoginseng (Burk. ) F. H. Chen. |
| 功用: | Treatment of hemoptysis, hematemesis, epistaxis, hematochezia, abnormal uterine bleeding, traumatic bleeding, pricking pain in the chest and abdomen, traumatic swelling and pain. |
| 适用症: | 1. Flavonoid glycoside, one of its components, increases coronary flow, reduces myocardial oxygen consumption and lowers arterial pressure.2.Cardiotonic on frogs' hearts in vitro; low concentration of its extract exerts a vasoconstrictive effect on the vessels of frogs' leg and high concentration, vasodilative3. Its liquid extract shortens clotting time and exerts hemostatic effect in rabbit. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 41753-43-9 | 人参皂苷Rb1 | Ginsenoside Rb1 | 9898279 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| BAK1 | BAK; BAK-LIKE; BCL2L7; CDN1 | 6p21.31 | 24622841 |
| BAX | BCL2L4 | 19q13.33 | 21194832 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21194832 |
| CASP8 | ALPS2B; CAP4; Casp-8; FLICE; MACH; MCH5 | 2q33.1 | 24622841 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 24622841 |
| FAS | ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6 | 10q23.31 | 24622841 |
| FASN | FAS; OA-519; SDR27X1 | 17q25.3 | 24622841 |
| KDR | CD309; FLK1; VEGFR; VEGFR2 | 4q12 | 29465315 |
| NFKB1 | CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB | 4q24 | 21194832 |
| PIGU | CDC91L1; GAB1; GPIBD21; NEDBSS | 20q11.22 | 29465315 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Colorectal Neoplasms | group | 21194832 |
| Corneal Neovascularization | disease | 29465315 |
| Prostatic Neoplasms | group | 29457293 |
