1. 药材主信息
| 中文名称: | 海藻 |
| 英文名称: | seaweed |
| 拉丁名称: | Sargassum |
| 使用部位: | - |
| 功用: | To soften indurated mass, to eliminate phlegm and dissipate modulation, and to induce diuresis. |
| 适用症: | 1. Prevent and treat hypothyroidism caused by deficiency of iodine.2. Its aqueous infusion can lower blood pressure and inhibit the growth of trichophyton.3. Causing atrophy of mammary gland and decreasing milk secretion. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 26532-66-1 | - | (1S,2R,4aS,6aR,6aS,6bR,8R,8aR,10R,11R,12aR,14bS)-8,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid | 69569689 |
| 18449-41-7 | - | (4R)-2alpha,3beta,6beta,23-Tetrahydroxyurs-12-en-28-oic acid | 6710742 |
| 934-34-9 | 2-羟基苯并噻唑 | 2(3H)-Benzothiazolone | 13625 |
| 4295-36-7 | 2,3-二氢-1H-喹啉-4-酮 | 2,3-dihydro-1H-quinolin-4-one | 117158 |
| 99-96-7 | 对羟基苯甲酸 | 4-Hydroxybenzoic acid | 135 |
| 13161-32-5 | 4-羟基异苯并呋喃-1(3H)-酮 | 4-Hydroxyisobenzofuran-1(3H)-one | 12662077 |
| 464-92-6 | 积雪草酸 | Asiatic Acid | 119034 |
| 125265-68-1 | 积雪草苷B | Asiaticoside B | 91618002 |
| 58115-31-4 | 橙黄胡椒酰胺乙酸酯 | Aurantiamide | 185904 |
| 464-72-2 | 苯频哪醇 | Benzopinacol | 94766 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ACACA | ACAC; ACACAD; ACC; ACC1; ACCA | 17q12 | 28358365 |
| BAX | BCL2L4 | 19q13.33 | 29228978 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 29228978 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 29228978 |
| COL11A2 | DFNA13; DFNB53; FBCG2; HKE5; OSMEDA; OSMEDB; PARP; STL3 | 6p21.32 | 29228978 |
| HGF | DFNB39; F-TCF; HGFB; HPTA; SF | 7q21.11 | 26750154 |
| IL6 | BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6 | 7p15.3 | 29228978 |
| MAPK1 | ERK; ERK-2; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41; p41mapk; p42-MAPK | 22q11.22 | 29228978 |
| MMP9 | CLG4B; GELB; MANDP2; MMP-9 | 20q13.12 | 22511009 |
| NFKB1 | CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB | 4q24 | 29228978 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Brain Infarction | disease | 22511009 |
| Colitis | disease | 28358365 |
| Inflammation | phenotype | 29228978 |
| Pulmonary Fibrosis | disease | 26750154 |
