1. 药材主信息
| 中文名称: | 瓜蒌 |
| 英文名称: | Trichosanthes Kirilowii Maxim |
| 拉丁名称: | - |
| 使用部位: | - |
| 功用: | - |
| 适用症: | Angina pectoris, lung heat cough, chest impediment, diabetes mellitus, acute mastitis, constipation, swelling toxin of welling abscess and sore. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 87-72-9 | L-(+)-阿拉伯糖 | - | 439195 |
| 50-69-1 | D-核糖，D-脆核糖,异性树胶糖 | (2R,3R,4R)-2,3,4,5-tetrahydroxypentanal | 5311110 |
| 3615-41-6 | L-鼠李糖 | (2R,3R,4S,5S)-2,3,4,5-tetrahydroxyhexanal | 19233 |
| 59-23-4 | - | (2R,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexanal | 3037556 |
| 13360-61-7 | 1-十五碳烯 | 1-Pentadecene | 25913 |
| 502-73-8 | 16-三十一酮 | 16-Hentriacontanone | 94741 |
| 18829-56-6 | 反-2-壬烯醛 | 2-Nonenal | 5283335 |
| 521-03-9 | - | 24-Ethyl-5alpha-cholest-7-en-3beta-ol | 131751392 |
| 7541-49-3 | 叶绿醇 | 3,7,11,15-Tetramethyl-2-hexadecen-1-OL | 5366244 |
| 90111-34-5 | 4-羟基-2-甲氧基苯甲酸 | 4-Hydroxy-2-methoxybenzoic acid | 12695575 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| ACLY | ACL; ATPCL; CLATP | 17q21.2 | 24690568 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 21440986 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 30825187 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Bone neoplasms | group | 21440986 |
| Carcinogenesis | phenotype | 28027595 |
| Colitis | disease | 25281414 |
| Diabetes | disease | 28049156 |
| Diabetes | disease | 28707095 |
| Diabetes Mellitus | group | 25411288 |
| Diabetes Mellitus, Experimental | disease | 26185015 |
| Diabetic Cardiomyopathies | disease | 26185015 |
| Glucose tolerance test | phenotype | 25411288 |
| Head and Neck Neoplasms | group | 30339884 |
