1. 药材主信息
| 中文名称: | 枸橘 |
| 英文名称: | Trifoliate-orange |
| 拉丁名称: | Poncirus trifoliata |
| 使用部位: | unripe fruit |
| 功用: | To break qi and dissipate binds, course liver and resolve depression. |
| 适用症: | Binding depression of liver qi , mammary consumption, mounting qi, qi stagnation, distention fullness in stomach duct and abdomen, pain in stomach duct, constipation, prolapse of uterus, prolapse of rectum. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 751-29-1 | - | (2E)-3-[(3aS,5aR,6R,7R,9aR,9bR,10aS)-3-(Furan-3-yl)-7-(2-hydroxypropan-2-yl)-3a,6,9a-trimethyl-1,9-dioxododecahydronaphtho[2,1-c]oxireno[d]pyran-6-yl]prop-2-enoic acid | 54611038 |
| 642-05-7 | 别欧前胡素 | Alloimperatorin | 69502 |
| 118-65-0 | (-)-异丁香烯 | Isocaryophyllene | 5281522 |
| 1180-71-8 | 柠檬苦素（吴茱萸内酯） | Limonin | 179651 |
| 10236-47-2 | 柚皮苷 | Naringin | 442428 |
| 14259-46-2 | 芸香柚皮苷 | Narirutin | 442431 |
| 523-59-1 | 邪蒿素 | Seselin | 68229 |
| 83-95-4 | 茵芋碱（β-花椒碱） | Skimmianine | 6760 |
| 93-39-0 | 茵芋苷 | Skimmin | 99693 |
| 2009-24-7 | 花椒毒酚 | Xanthotoxol | 65090 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25047426 |
| AURKA | AIK; ARK1; AURA; BTAK; PPP1R47; STK15; STK6; STK7 | 20q13.2 | 25047426 |
| BAX | BCL2L4 | 19q13.33 | 25047426 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 25047426 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 25047426 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 25047426 |
| CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | 3p22.1 | 25047426 |
| CYC1 | MC3DN6; UQCR4 | 8q24.3 | 25047426 |
| GSK3B | - | 3q13.33 | 25047426 |
| IFNG | IFG; IFI | 12q15 | 30338847 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinogenesis | phenotype | 25047426 |
| Colonic Neoplasms | group | 25047426 |
| Inflammation | phenotype | 30338847 |
| Sepsis | disease | 30338847 |
