1. 药材主信息
| 中文名称: | 狗脊 |
| 英文名称: | Cochinchina Cudrania |
| 拉丁名称: | Cudrania cochinchinensis |
| 使用部位: | root |
| 功用: | To dispel wind and free network vessels, clear heat and remove damp, resolve toxin and disperse swelling. |
| 适用症: | Wind-damp impediment pain, knocks and falls, jaundice, parotitis, phthisis, gastric ulcer, duodenal ulcer, strangury-turbidity, tympanites, menstrual block, taxation damage and coughing of blood, clove sore and swollen welling abscess. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 480-41-1 | - | (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one | 667495 |
| 20245-39-0 | 1,3,7-Trihydroxy-2-prenylxanthone | 1,3,7-Trihydroxy-2-prenylxanthone | 5495920 |
| 36190-95-1 | 3''-O-甲基香豌豆苷元 | 3'-O-Methylorobol | 5319744 |
| 16265-56-8 | 6-Deoxyjacareubin | 6-Deoxyjacareubin | 5281629 |
| 34086-50-5 | 猫尾草异黄酮 | Alpinumisoflavone | 5490139 |
| 519-40-4 | - | Aspidinol | 122841 |
| 484-20-8 | 佛手柑内酯 | Bergapten | 2355 |
| 63596-94-1 | - | Cudranone | 191694 |
| 520-18-3 | 山柰素（山柰酚） | Kaempferol | 5280863 |
| 5848-14-6 | MACLURAXANTHONE | Macluraxanthone | 5281646 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27710830 |
| ICMT | HSTE14; MST098; MSTP098; PCCMT; PCMT; PPMT | 1p36.31 | 27710830 |
| IFNG | IFG; IFI | 12q15 | 21748601 |
| IL2 | IL-2; TCGF; lymphokine | 4q27 | 21748601 |
| MAP2K7 | JNKK2; MAPKK7; MEK; MEK 7; MKK7; PRKMK7; SAPKK-4; SAPKK4 | 19p13.2 | 27710830 |
| MTOR | FRAP; FRAP1; FRAP2; RAFT1; RAPT1; SKS | 1p36.22 | 27710830 |
| NFE2L2 | HEBP1; IMDDHH; NRF2; Nrf-2 | 2q31.2 | 30527894 |
| NFKB1 | CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB | 4q24 | 31758699 |
| NLRP3 | AGTAVPRL; AII; AVP; C1orf7; CIAS1; CLR1.1; DFNA34; FCAS; FCAS1; FCU; KEFH; MWS; NALP3; PYPAF1 | 1q44 | 31758699 |
| PKD2 | APKD2; PC2; PKD4; Pc-2; TRPP2 | 4q22.1 | 24116661 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Chronic liver disease | group | 21354229 |
| Colorectal Neoplasms | group | 27710830 |
| Lung Neoplasms | group | 21748601 |
| Necrosis | phenotype | 27710830 |
| Neuroblastoma | disease | 22459762 |
| Non-alcoholic Fatty Liver Disease | disease | 31758699 |
| Polycystic Kidney, Autosomal Dominant | disease | 24116661 |
