1. 药材主信息
| 中文名称: | 干地黄 |
| 英文名称: | Adhesive Rehmannia Dried Root |
| 拉丁名称: | Rehmannia glutinosa [Syn. Rehmannia glutinosa f. h |
| 使用部位: | dried root |
| 功用: | To enrich yin and clear heat, cool blood and supplement blood, lower blood sugar levels. |
| 适用症: | Diabetes mellitus, dermatitis, rheumatism, diphtheria, acute tonsillitis, febrile diseases with vexation and thirst, steaming bone taxation fever, warm disease macular eruption, blood ejection due to blood heat, spontaneous external bleeding due to blood heat, flooding and spotting due to blood heat, hematuria due to blood heat, hematochezia due to blood heat, anemia with yellow complexion, palpitation and dizziness, blood depletion and amenorrhea. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 506-30-9 | 花生酸 | - | 10467 |
| 52949-83-4 | - | (2S,3S,4R,5R,6S)-6-[[(4aS,7S,7aR)-7-hydroxy-7-methyl-4a,5,6,7a-tetrahydro-1H-cyclopenta[c]pyran-1-yl]oxy]-2-(hydroxymethyl)oxane-2,3,4,5-tetrol | 6452750 |
| 13360-61-7 | 1-十五碳烯 | 1-Pentadecene | 25913 |
| 502-73-8 | 16-三十一酮 | 16-Hentriacontanone | 94741 |
| 17587-33-6 | Trans,Trans-2,6-Nonadienal | 2,6-Nonadienal, (E,E)- | 636687 |
| 124168-04-3 | 6-O-香草酰基筋骨草醇 | 6-O-Vanilloylajugol | 14396664 |
| 82509-41-9 | 8-表马钱子苷酸 | 8-Epiloganic acid | 158144 |
| 41547-82-4 | 腺苷 | Adenosine | 60961 |
| 41547-82-4 | 腺苷 | Adenosine | 60961 |
| 74545-79-2 | - | Aloeresin A | 5317657 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 31378931 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 23127783 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 29284152 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 25950476 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| ATF6 | ACHM7; ATF6A | 1q23.3 | 28655643 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Acute kidney injury | disease | 28616865 |
| Alzheimer's Disease | disease | 30578827 |
| Cardiac Hypertrophy | phenotype | 26845648 |
| Cardiomegaly | phenotype | 26845648 |
| Chromosome Aberrations | group | 23701745 |
| Colitis | disease | 28655643 |
| Diabetes | disease | 28707095 |
| Diabetes Mellitus | group | 25411288 |
| Diabetes Mellitus, Experimental | disease | 25950476 |
| Diabetes Mellitus, Experimental | disease | 29284152 |
