1. 药材主信息
| 中文名称: | 冬瓜子 |
| 英文名称: | Benincasae Semen |
| 拉丁名称: | - |
| 使用部位: | - |
| 功用: | - |
| 适用症: | Phlegm-heat cough, pulmonary welling abscess, intestinal welling abscess, white turbidity, vaginal discharge, beriberi, edema, strangury syndrome. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 17334-55-3 | - | (1aR,7R,7aR,7bS)-1,1,7,7a-tetramethyl-2,3,5,6,7,7b-hexahydro-1aH-cyclopropa[a]naphthalene | 15560278 |
| 480-41-1 | - | (2R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one | 667495 |
| 20489-11-6 | Nardosinonediol | (3R,4aR,5R)-3-hydroxy-4-(2-hydroxypropan-2-yl)-4a,5-dimethyl-2,3,4,5,6,7-hexahydronaphthalen-1-one | 134715257 |
| 83-56-7 | 1,5-二羟基萘 | 1,5-Dihydroxynaphthalene | 6749 |
| 19380-05-3 | - | 2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one, 9,10-dihydro-9-hydroxy-8,8-dimethyl-, (R)- | 759302 |
| 496-72-0 | 3,4-二氨基甲苯 | 3,4-Diaminotoluene | 10332 |
| 7488-99-5 | α-胡萝卜素 | alpha-Carotene | 6419725 |
| 523-50-2 | 异补骨脂素 | Angelicin | 10658 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 27710830 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| BAX | BCL2L4 | 19q13.33 | 28456683 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 28456683 |
| CHDH | - | 3p21.1 | 31255657 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Adenoma | group | 21693628 |
| Birth Weight | phenotype | 27655442 |
| Body mass index | phenotype | 27655442 |
| Brain Ischemia | disease | 30014516 |
| Brain Ischemia | disease | 24884571 |
| Carcinogenesis | phenotype | 24169354 |
| Carcinoma | group | 24169354 |
| Choline Deficiency | disease | 31120771 |
| Chronic liver disease | group | 21354229 |
| Colitis | disease | 28456683 |
