1. 药材主信息
| 中文名称: | 棣棠花 |
| 英文名称: | Japanese Kerria Flower |
| 拉丁名称: | Kerria japonica |
| 使用部位: | flower or branchlet-leaf |
| 功用: | To relieve cough and transform phlegm, disinhibit damp and disperse swelling, resolve toxin. |
| 适用症: | Cough, wind-damp impediment pain, postpartum vacuity taxation, edema, inhibited urination, indigestion, swelling toxin of welling abscess and flat abscess, eczema, urticaria. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 546-43-0 | 土木香内酯 | Alantolactone | 72724 |
| 13323-48-3 | Heliangin | CID 12310408 | 12310408 |
| 303-45-7 | 棉酚 | Gossypol | 3503 |
| 19083-00-2 | 纤细薯蓣皂苷 | Gracillin | 159861 |
| 547-17-1 | 堆心菊素 | Helenien | 5281240 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| CYCS | CYC; HCS; THC4 | 7p15.3 | 28701209 |
| IKBKB | IKK-beta; IKK2; IKKB; IMD15; IMD15A; IMD15B; NFKBIKB | 8p11.21 | 28701209 |
| NDUFA5 | B13; CI-13KD-B; CI-13kB; NUFM; UQOR13 | 7q31.32 | 31649278 |
| NFKB1 | CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB | 4q24 | 27658462 |
| NFKB1 | CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB | 4q24 | 28701209 |
| NFKB1 | CVID12; EBP-1; KBF1; NF-kB; NF-kB1; NF-kappa-B1; NF-kappaB; NF-kappabeta; NFKB-p105; NFKB-p50; NFkappaB | 4q24 | 31323885 |
| PTGS2 | COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2 | 1q31.1 | 28701209 |
| PTPRU | FMI; PCP-2; PTP; PTP-J; PTP-PI; PTP-RO; PTPPSI; PTPRO; PTPU2; R-PTP-PSI; R-PTP-U; hPTP-J | 1p35.3 | 25434800 |
| SDHB | CWS2; IP; PGL4; SDH; SDH1; SDH2; SDHIP | 1p36.13 | 31649278 |
| STAT3 | ADMIO; ADMIO1; APRF; HIES | 17q21.2 | 25434800 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Glioblastoma Multiforme | disease | 28701209 |
| Infarction, Middle Cerebral Artery | disease | 31323885 |
