1. 药材主信息
| 中文名称: | 地锦草 |
| 英文名称: | all - grass of Humifuse Euphorbia |
| 拉丁名称: | Herba Euphorbiae humifusae |
| 使用部位: | whole herb |
| 功用: | To remove toxic heat and to arrest bleeding by reducing heat in blood. |
| 适用症: | Dysentery, enteritis, hemoptysis, hematuria, hematochezia, flooding and spotting, swollen welling abscess, sore and boil. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 83-56-7 | 1,5-二羟基萘 | 1,5-Dihydroxynaphthalene | 6749 |
| 21637-25-2 | - | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one | 51402807 |
| 496-72-0 | 3,4-二氨基甲苯 | 3,4-Diaminotoluene | 10332 |
| 6665-67-4 | 5,4 '-二羟基黄酮 | 4',5-Dihydroxyflavone | 165521 |
| 480-10-4 | 紫云英苷 | Astragalin | 5282102 |
| 494-56-4 | - | Ayapin | 3083597 |
| 1616-93-9 | β-香树脂素乙酸酯 | beta-Amyrin acetate | 92156 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 470-82-6 | 桉油精；桉叶素 | Eucalyptol | 2758 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 29235094 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 29235094 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 21445586 |
| ACACA | ACAC; ACACAD; ACC; ACC1; ACCA | 17q12 | 30630510 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 23684930 |
| BAX | BCL2L4 | 19q13.33 | 28456683 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 28456683 |
| BNIP3 | NIP3 | 10q26.3 | 28838842 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 26418626 |
| CASR | CAR; EIG8; FHH; FIH; GPRC2A; HHC; HHC1; HYPOC1; NSHPT; PCAR1; hCasR | 3q13.33-q21.1 | 21445586 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Alzheimer's Disease | disease | 30447302 |
| Body Weight | phenotype | 24559844 |
| Cholestasis | disease | 29235094 |
| Colitis | disease | 28456683 |
| Colitis | disease | 22677088 |
| Crohn Disease | disease | 22677088 |
| Edema | phenotype | 28240768 |
| Electrocardiography | phenotype | 23058930 |
| Helicobacter Infections | group | 29566160 |
| Hyperlipidemia | disease | 23058930 |
