科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 大飞扬草
英文名称: Garden Euphorbia
拉丁名称: Euphorbia hirta
使用部位: whole herb with root
功用: To clear heat and resolve toxin, percolate damp and relieve itch, free milk.
适用症: Acute enteritis, bacillary dysentery, strangury, hematuria, pulmonary welling abscess, mammary welling abscess, clove sore, toxin swelling, eczema, foot lichen, itchy skin.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
519-23-3 椭圆玫瑰树碱 Ellipticine 3213

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 23684930
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 31608279
AKT2 HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA 19q13.2 31608279
BNIP3 NIP3 10q26.3 28838842
CASP3 CPP32; CPP32B; SCA-1 4q35.1 26418626
CYCS CYC; HCS; THC4 7p15.3 26418626
CYP2J2 CPJ2; CYPIIJ2 1p32.1 24216999
CYP4F2 CPF2 19p13.12 24216999
DNM1L DLP1; DRP1; DVLP; DYMPLE; EMPF; EMPF1; HDYNIV; OPA5 12p11.21 31914641
EPHX2 ABHD20; CEH; SEH 8p21.2-p21.1 24216999

4. 相关疾病

疾病名称 疾病类型 参考文献
Colitis disease 22677088
Crohn Disease disease 22677088
Electrocardiography phenotype 23058930
Helicobacter Infections group 29566160
Hyperlipidemia disease 23058930
Hypertrophy phenotype 23058930
Mitochondrial Swelling phenotype 26418626
Myocardial Infarction disease 23058930
Necrosis phenotype 28838842
Pain phenotype 22646533