1. 药材主信息
| 中文名称: | 川乌 |
| 英文名称: | root of Common Monkshood |
| 拉丁名称: | Radix Aconiti |
| 使用部位: | - |
| 功用: | To relieve rheumatic conditions and alleviate pain by warming the channels. |
| 适用症: | Treatment of joint pain in rheumatic or rheumatoid arthritis, epigastric pain with cold sensation, or abdominal colic due to cold, also used as an analgesic in anaesthesis. |
| 毒副作用: | Slightly Toxic |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 7785-70-8 | (1R)-(+)-alpha-蒎烯 | (+)-alpha-Pinene | 82227 |
| 28976-67-2 | - | (-)-beta-Curcumene | 14014430 |
| 15219-93-9 | - | (2S,3S,4S,5R)-2,5-bis(hydroxymethyl)-2-methoxyoxolane-3,4-diol | 6325664 |
| 5655-61-8 | - | (2S,4R)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl acetate | 44630108 |
| 155320-20-0 | - | (S)-Sulforaphane | 10419733 |
| 22513-81-1 | - | 1,22-Docosanediol | 347359 |
| 5309-18-2 | 1,7-Dimethoxynaphthalene | 1,7-Dimethoxynaphthalene | 79197 |
| 1454-85-9 | 1-十七烷醇 | 1-Heptadecanol | 15076 |
| 90-12-0 | - | 1-Methylnaphthalene | 7002 |
| 111-87-5 | 1-辛醇 | 1-Octanol | 957 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| ADRB2 | ADRB2R; ADRBR; B2AR; BAR; BETA2AR | 5q32 | 26746354 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 26746354 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 26746354 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Aging | phenotype | 24932939 |
| Alzheimer's Disease | disease | 31560162 |
| Diabetes | disease | 28707095 |
| Diabetes Mellitus | group | 25411288 |
| Down Syndrome | disease | 24932939 |
| Glucose tolerance test | phenotype | 25411288 |
| Hyperglycemia | disease | 23471488 |
| Hyperglycemia | disease | 28707095 |
| Insulin Resistance | phenotype | 25411288 |
| Liver diseases | group | 24107776 |
