1. 药材主信息
| 中文名称: | 补骨脂 |
| 英文名称: | Malaytea Scurfpea |
| 拉丁名称: | Psoralea corylifolia |
| 使用部位: | fruit |
| 功用: | To supplement kidney and invigorate yang , accept qi and calm asthma, warm spleen and check diarrhea. |
| 适用症: | Fracture, osteomalacia, osteoporosis, kidney yang vacuity, cold pain in lumbus and knees, impotence and emission, frequent urination, enuresis, kidney qi insecurity, vacuity asthma, spleen-kidney vacuity, chronic diarrhea, white patch wind, alopecia areata, psoriasis. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 523-50-2 | 异补骨脂素 | Angelicin | 10658 |
| 84575-13-3 | Bakuchalcone | Bakuchalcone | 6476086 |
| 10309-37-2 | 补骨脂酚 | Bakuchiol | 5468522 |
| 28448-85-3 | 补骨脂查尔酮 | Bavachalcone | 6450879 |
| 41743-38-8 | Bavachromene | Bavachromene | 5321800 |
| 53947-92-5 | 补骨脂宁 | Corylin | 5316097 |
| 20784-50-3 | 补骨脂乙素 | Isobavachalcone | 5281255 |
| 20784-50-3 | 补骨脂乙素 | Isobavachalcone | 5281255 |
| 298-81-7 | 花椒毒素 | Methoxsalen | 4114 |
| 544-63-8 | 肉豆蔻酸 | Myristic Acid | 11005 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| ABCB11 | ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP | 2q31.1 | 24107776 |
| ABCC2 | ABC30; CMOAT; DJS; MRP2; cMRP | 10q24.2 | 24107776 |
| ABCG5 | STSL; STSL2 | 2p21 | 24107776 |
| ABCG8 | GBD4; STSL; STSL1 | 2p21 | 24107776 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 31534518 |
| APP | AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 | 21q21.3 | 24107941 |
| BACE1 | ASP2; BACE; HSPC104 | 11q23.3 | 24107941 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 28588318 |
| CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | 3p22.1 | 31965654 |
| DGKD | DGK-delta; DGKdelta; dgkd-2 | 2q37.1 | 28707095 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinogenesis | phenotype | 28588318 |
| Diabetes | disease | 28707095 |
| Hyperglycemia | disease | 28707095 |
| Liver diseases | group | 24107776 |
| Liver neoplasms | group | 29749376 |
| Metabolic Diseases | group | 31534518 |
| Osteoporosis | disease | 31965654 |
| Pain | phenotype | 29947134 |
| Prostatic Neoplasms | group | 28588318 |
| Skin Pigmentation | phenotype | 29947134 |
