科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 扁豆
英文名称: Niger Bean
拉丁名称: Lablab niger
使用部位: Dolichos lablab L.
功用: 1. Treatment of deficient spleen not transforming and transporting water manifested as lassitude, poor appetite, loose stool or diarrhea, or leukorrhea due to downward flowing of turbid dampness. Hyacinth bean (Biandou) is used with Ginseng (Renshen), White atractylodes (Baizhu) and Poria (Fuling) in the formula Shen Ling Baizhu San. 2. Treatment of disharmony of the spleen and stomach due to invasion from exogenous pathogenic summer-damp-heat manifested as vomiting and diarrhea. Hyacinth bean (Biandou) is used with Elsholtzia (Xiangru) and Magnolia bark (Houpo) in the formula Xiangru San.
适用症: Containing phytoagglutintin, trypsin and amylase inhibitors.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
7488-99-5 α-胡萝卜素 alpha-Carotene 6419725
7235-40-7 β-胡萝卜素 Beta-Carotene 5280489
512-69-6 D-棉子糖 Raffinose 439242
153-18-4 芦丁 Rutin 5280805
83-48-7 豆甾醇 Stigmasterol 5280794
57-50-1 蔗糖 Sucrose 5988
1637-39-4 反玉米素 trans-Zeatin 449093
144-68-3 玉米黄素 Zeaxanthin 5280899

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
ABCB11 ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP 2q31.1 24107776
ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP 10q24.2 24107776
ABCG5 STSL; STSL2 2p21 24107776
ABCG8 GBD4; STSL; STSL1 2p21 24107776
APP AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2; preA4 21q21.3 24107941
BACE1 ASP2; BACE; HSPC104 11q23.3 24107941
CD69 AIM; BL-AC/P26; CLEC2C; EA1; GP32/28; MLR-3 12p13.31 24813229
IL13 IL-13; P600 5q31.1 24813229
IL2 IL-2; TCGF; lymphokine 4q27 24813229
IL4 BCGF-1; BCGF1; BSF-1; BSF1; IL-4 5q31.1 24813229

4. 相关疾病

疾病名称 疾病类型 参考文献
Leukocytosis phenotype 24813229
Liver diseases group 24107776
Lymphoma, Non-Hodgkin disease 22550343