科华智慧(深圳)创新药物研发有限公司     西北农林科技大学深圳研究院    联合开发

1. 药材主信息

中文名称: 板蓝根
英文名称: Root of Dyers Woad.
拉丁名称: Radix Isatidis seu Baphicacanthi
使用部位: root
功用: To remove toxic heat, to reduce heat in blood, and to soothe sore throat.
适用症: Epidemic encephalitis, measles papulis, parotitis, influenza, warm toxin macular eruption, ardent fever with headache, massive head scourge, throat pain, maculopapular eruption, epidemic parotitis, erysipelas, hepatitis, swelling toxin of sore and welling abscess.
毒副作用: -

2. 相关成分

CAS号 中文名称 英文名称 参考文献
17283-81-7 Dihydro-Beta-Ionone - 519382
492-62-6 - - 79025
111003-33-9 - (-)-Taxifolin 712316
20307-14-6 - (2R,3R,5S,6S)-3,5-dihydroxy-2-(hydroxymethyl)-6-(1H-indol-3-yloxy)oxan-4-one 101529308
138865-23-3 PBD--5,11-二酮 (S)-(+)-2,3-Dihydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-5,11(10H,11aH)-dione 677114
154-58-5 1,5-Anhydro-D-Sorbitol Crystalline 1,5-Anhydro-D-glucitol 64960
6765-39-5 1-十七碳烯 1-Heptadecene 23217
17608-07-0 - 1-Isothiocyanato-4-methylpentane 519452
67282-55-7 - 1-Methoxyindole-3-carbaldehyde 398554
27400-77-7 - 1-Nonadecene 29075

3. 相关靶点

基因靶点 基因别名 靶点位置 参考文献
ABCB11 ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4; SPGP 2q31.1 24107776
ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP 10q24.2 21445586
ABCC2 ABC30; CMOAT; DJS; MRP2; cMRP 10q24.2 24107776
ABCG5 STSL; STSL2 2p21 24107776
ABCG8 GBD4; STSL; STSL1 2p21 24107776
AGT ANHU; SERPINA8; hFLT1 1q42.2 21844078
AHR RP85; bHLHe76 7p21.1 22533375
AKR1B1 ADR; ALDR1; ALR2; AR 7q33 21712449
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 21871133
AKT1 AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA 14q32.33 24157255

4. 相关疾病