1. 药材主信息
| 中文名称: | 白花丹 |
| 英文名称: | Whiteflower Leadword |
| 拉丁名称: | Plumbago zeylanica |
| 使用部位: | whole herb and root |
| 功用: | To dispel wind and eliminate damp, move qi and quicken blood, resolve toxin and disperse swelling. |
| 适用症: | Wind-damp impediment pain, liver spleen enlargement, amenorrhea due to blood stasis, sprain from knocks and falls, swollen welling abscess and scrofula, scab and lichen with itching, poisonous snake bite. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 34341-27-0 | - | 3,3'-Biplumbagin | 183757 |
| 21890-57-3 | - | 3-Chloro-5-hydroxy-2-methylnaphthalene-1,4-dione | 338719 |
| 123-08-0 | 对羟基苯甲醛 | 4-Hydroxybenzaldehyde | 126 |
| 31525-76-5 | 5-甲氧基邪蒿素 | 5-Methoxyseselin | 290897 |
| 38412-47-4 | 2,5-二甲基-7-羟基色酮 | 7-Hydroxy-2,5-dimethyl-4H-1-benzopyran-4-one | 5316891 |
| 33927-59-2 | - | 8,8'-Biplumbagin | 633024 |
| 897-06-3 | - | Androsta-1,4-diene-3,17-dione | 13472 |
| 83-46-5 | β-谷甾醇 | Beta-Sitosterol | 222284 |
| 478-40-0 | - | Droserone | 442739 |
| 20175-85-3 | - | Elliptinone | 146680 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 24280585 |
| AKT1 | AKT; CWS6; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA | 14q32.33 | 29339720 |
| ALDH1A1 | ALDC; ALDH-E1; ALDH1; ALDH11; HEL-9; HEL-S-53e; HEL12; PUMB1; RALDH1 | 9q21.13 | 31693936 |
| BAX | BCL2L4 | 19q13.33 | 21982843 |
| BAX | BCL2L4 | 19q13.33 | 25444924 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 21982843 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 21982843 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 31493505 |
| CEBPA | C/EBP-alpha; CEBP | 19q13.11 | 29141998 |
| CTNNB1 | CTNNB; EVR7; MRD19; NEDSDV; armadillo | 3p22.1 | 31693936 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinogenesis | phenotype | 29339720 |
| Esophageal Neoplasms | group | 29339720 |
| Inflammation | phenotype | 24329519 |
| Inflammation | phenotype | 30338847 |
| Inflammatory Bowel Diseases | group | 31914614 |
| Lung Neoplasms | group | 24280585 |
| Lymphoma | group | 25444924 |
| Obesity | disease | 29141998 |
| Prostatic Neoplasms | group | 26808083 |
| Sepsis | disease | 30338847 |
