1. 药材主信息
| 中文名称: | 紫杉 |
| 英文名称: | Japanese Yew |
| 拉丁名称: | Taxus cuspidata |
| 使用部位: | branchlet-leaf |
| 功用: | To disinhibit urine and free channels, anticancer. |
| 适用症: | Kidney disease, diabetes mellitus, carcinoma of ovary, carcinoma of mammary glands. |
| 毒副作用: | - |
2. 相关成分
| CAS号 | 中文名称 | 英文名称 | 参考文献 |
| 18457-44-8 | 紫杉素 B | - | 10055179 |
| 18457-45-9 | 7-Deacetoxytaxinine J | - | 14466613 |
| 261613-72-3 | - | (R)-nonacosan-10-ol | 342803 |
| 220932-65-0 | 13-O-Cinnamoylbaccatin III | 13-O-Cinnamoylbaccatin III | 5321740 |
| 14787-34-9 | 5-Hydroxy-3,6,7,4'-tetramethoxyflavone | 5-Hydroxy-3,6,7,4'-tetramethoxyflavone | 5318355 |
| 27548-93-2 | 巴卡亭III | Baccatin III | 65366 |
| 71610-00-9 | - | Cephalomannine, analytical standard | 5281819 |
| 628-97-7 | 棕榈酸乙酯 | Ethyl palmitate | 12366 |
| 548-29-8 | 异落叶松脂素 | Isolariciresinol, (+)- | 160521 |
| 26194-57-0 | Isotaxiresinol | Isotaxiresinol | 9841162 |
3. 相关靶点
| 基因靶点 | 基因别名 | 靶点位置 | 参考文献 |
| AGT | ANHU; SERPINA8; hFLT1 | 1q42.2 | 21844078 |
| Atat1 | 0610011P08Rik; 2610008K08Rik; 2610110G12Rik; 3110080J08Rik; MEC-17; Mec17; TAT | 17|17 B1 | 28968698 |
| AURKA | AIK; ARK1; AURA; BTAK; PPP1R47; STK15; STK6; STK7 | 20q13.2 | 23348568 |
| BAX | BCL2L4 | 19q13.33 | 24080340 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 23681233 |
| BCL2 | Bcl-2; PPP1R50 | 18q21.33 | 28589243 |
| BCL2L1 | BCL-XL/S; BCL2L; BCLX; Bcl-X; PPP1R52 | 20q11.21 | 23681233 |
| CASP3 | CPP32; CPP32B; SCA-1 | 4q35.1 | 28589243 |
| CASP9 | APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56 | 1p36.21 | 28589243 |
| CCL2 | GDCF-2; HC11; HSMCR30; MCAF; MCP-1; MCP1; SCYA2; SMC-CF | 17q12 | 23726937 |
4. 相关疾病
| 疾病名称 | 疾病类型 | 参考文献 |
| Carcinogenesis | phenotype | 28589243 |
| Carcinogenesis | phenotype | 25827073 |
| Carcinoma, Transitional Cell | disease | 20682548 |
| Fibrosis | phenotype | 21984124 |
| Hyperalgesia | phenotype | 21145656 |
| Liver neoplasms | group | 29748662 |
| Longevity | phenotype | 26913604 |
| Lung Neoplasms | group | 31779616 |
| Lung Neoplasms | group | 28991240 |
| Lung Neoplasms | group | 28589243 |
